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Commitments and Contingencies (Details) - USD ($)
$ in Thousands
3 Months Ended
Feb. 27, 2017
Jan. 27, 2017
Mar. 31, 2018
Apr. 27, 2018
Dec. 31, 2017
Recorded Unconditional Purchase Obligation [Line Items]          
Initial term of lease 63 months        
Lease commencement date Jan. 01, 2018        
Buy-out of obligations lease $ 600        
Common stock, aggregate amount     $ 62   $ 58
Lorem Vascular [Member] | Subsequent Event [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Percentage of common stock to be purchased       5.00%  
Common stock, aggregate amount       $ 5,000  
Japan Lease [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Initial term of lease   61 months      
Lease commencement date     Apr. 15, 2017    
Pre-clinical Research Study Obligations [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Contractual obligation, due in next twelve months     $ 2,200    
Contractual obligation     3,900    
Roche Diagnostics Corporation [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Purchase obligation     4,000    
Purchase obligation, due in next twelve months     $ 1,000