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Commitments and Contingencies (Details) - USD ($)
$ in Thousands
6 Months Ended
Feb. 27, 2017
Jun. 30, 2018
Apr. 27, 2018
Dec. 31, 2017
Jan. 27, 2017
Recorded Unconditional Purchase Obligation [Line Items]          
Initial term of lease 63 months        
Lease commencement date Jan. 01, 2018        
Buy-out of obligations lease $ 600        
Common stock, aggregate amount   $ 62   $ 58  
Lorem Vascular [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Percentage of common stock to be purchased     5.00%    
Common stock, aggregate amount     $ 5,000    
Japan Lease [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Initial term of lease         61 months
Lease commencement date   Apr. 15, 2017      
Pre-clinical Research Study Obligations [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Contractual obligation, due in next twelve months   $ 1,900      
Contractual obligation   $ 3,500