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Summary of Significant Accounting Policies - Additional Information (Details) $ / shares in Units, shares in Millions | 1 Months Ended | 12 Months Ended |
--- | --- | --- | ---
May 31, 2013 | Dec. 31, 2018 USD ($) Obligation Customer Segment $ / shares shares | Dec. 31, 2017 USD ($) Customer Licensee Segment shares | Dec. 31, 2016 USD ($)
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Cash equivalents investments with original maturities |  | $ 0 | $ 0 |
Impairment loss |  | 0 | 0 |
Acquired technology intangible assets |  | 9,400,000 |  |
Useful life (in years) | 11 years |  |  |
Amortization expense |  | 1,250,000 | 1,240,000 |
2019 |  | 1,200,000 |  |
2020 |  | 1,200,000 |  |
2021 |  | 1,200,000 |  |
2022 |  | 1,200,000 |  |
Thereafter |  | 900,000 |  |
Accumulated amortization on intangible assets |  | $ 5,900,000 | 4,700,000 |
Number of performance obligation | Obligation |  | 1 |  |
Payment terms with customers |  | The Company’s contracts do not involve financing elements as payment terms with customers are less than one year. |  |
Revenue recognized |  | $ 3,671,000 | 2,689,000 |
Qualifying expenditures related to research |  | 2,700,000 | 3,500,000 |
Interest or penalties related to income tax matters |  | $ 0 | $ 0 |
Number of operating segment | Segment |  | 1 | 1 |
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares |  | 13.7 | 0.5 |
Restricted cash |  | $ 40,000 | $ 675,000 | $ 400,000
Cash, cash equivalents |  | $ 5,261,000 | $ 9,550,000 | $ 12,600,000
Outstanding Warrants [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares |  | 8.9 |  |
Options and Restricted Stock [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares |  | 0.1 |  |
Preferred Stock and Restricted Stock Awards [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Dilutive securities excluded from the calculations of diluted loss per share (in shares) | shares |  | 4.7 |  |
Customer Concentration Risk [Member] | Product Revenue [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Number of customers | Customer |  | 2 | 5 |
Concentration risk percentage |  | 60.00% | 68.00% |
Customer Concentration Risk [Member] | Accounts Receivable [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Number of customers | Customer |  | 2 | 1 |
Concentration risk percentage |  | 70.00% | 77.00% |
Number of licensee | Licensee |  |  | 1 |
Royalty [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Revenue recognized |  | $ 1,000,000 |  |
Development [Member] | BARDA Contract [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Revenue recognized |  | $ 3,000,000 | $ 3,700,000 |
2018 Rights Offering [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Redemption price of warrant prior to expiration | $ / shares |  | $ 0.01 |  |
Common stock price per share for warrant redemption | $ / shares |  | $ 3.63 |  |
Number of consecutive trading days for warrant redemption |  | 20 days |  |
Warrants liability fair value |  | $ 900,000 | 3,100,000 |
Clinical Technology [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Amortization expense |  | $ 1,200,000 | 1,200,000 |
Minimum [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Useful lives of the assets |  | 3 years |  |
Maximum [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Useful lives of the assets |  | 5 years |  |
Letter of Credit [Member] |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |
Letters of credit amount pursuant to lease agreement |  | $ 40,000 | $ 700,000 |

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