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Composition of Certain Financial Statement Captions - Accounts Payable and Accrued Expenses (Details) - USD ($) $ in Thousands | Dec. 31, 2018 | Dec. 31, 2017
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Accounts Payable and Accrued Expenses [Abstract] |  |
Accrued expenses | $ 1,191 | $ 1,599
Accounts payable | 720 | 1,297
Accrued payroll and bonus | 554 | 810
Accrued legal fees | 186 | 509
Accrued vacation | 192 | 64
Accrued R&D studies | 230 | 286
Other current liabilities | 284 | 225
Accounts payable and accrued expenses, Total | $ 3,357 | $ 4,790

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