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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017
Cash flows from operating activities: |  |
Net loss | $ (12,634) | $ (22,686)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 2,004 | 2,151
Amortization of deferred financing costs and debt discount | 578 | 707
In process research and development acquired from Azaya Therapeutics | 0 | 1,686
Change in fair value of warrants | (2,233) | 0
Allocation of issuance cost associated with warrants | 470 | 0
Provision for doubtful accounts | 18 | 0
Provision for excess inventory | 463 | 340
Share-based compensation expense | 355 | 753
Loss (gain) on asset disposal | 36 | (42)
Increases (decreases) in cash caused by changes in operating assets and liabilities: |  |
Accounts receivable | (173) | 1,129
Inventories | 475 | 251
Other current assets | 85 | (593)
Other assets | 23 | (94)
Accounts payable and accrued expenses | (1,532) | (1,817)
Deferred revenues | 73 | (3)
Long-term deferred rent and other | 17 | 90
Net cash used in operating activities | (11,975) | (18,128)
Cash flows from investing activities: |  |
Proceeds from sale of assets | 0 | 113
Net cash used in investing activities | (133) | (1,383)
Cash flows from financing activities: |  |
Principal payments on long-term obligations | 0 | (4,720)
Financed capital expenditures | (66) | 0
Proceeds from sale of common and preferred stock | 8,766 | 23,613
Costs from sale of common and preferred stock | (1,532) | (2,078)
Net cash provided by financing activities | 7,168 | 16,815
Effect of exchange rate changes on cash and cash equivalents | 16 | 11
Net decrease in cash and cash equivalents | (4,924) | (2,685)
Cash, cash equivalents, and restricted cash at beginning of period | 10,225 | 12,910
Cash, cash equivalents, and restricted cash at end of period | 5,301 | 10,225
Cash paid during period for: |  |
Interest | 1,331 | 1,364
Supplemental schedule of non-cash investing and financing activities: |  |
Conversion of preferred stock into common stock | 8 | 23
Fair value of Series C and Series B Convertible Preferred Stock beneficial conversion feature | 2,487 | 3,977
Property Plant And Equipment Excluding Research Lab Equipment And Leasehold Improvements [Member] |  |
Cash flows from investing activities: |  |
Purchases of property and equipment /long-lived assets | (133) | (295)
Assets Purchased from Azaya Therapeutics, Inc. [Member] |  |
Cash flows from investing activities: |  |
Purchases of property and equipment /long-lived assets | 0 | (1,201)
Supplemental schedule of non-cash investing and financing activities: |  |
Common stock issued in payment for the assets acquired | $ 0 | $ 2,311

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- Definition The cash inflow from the sale of property, plant and equipment (capital expenditures), software, and other intangible assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 12 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3179-108585 + Details
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- Definition Amount of expense related to write-down of receivables to the amount expected to be collected. Includes, but is not limited to, accounts receivable and notes receivable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 220 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.5) -URI http://asc.fasb.org/extlink&oid=115205541&loc=SL114868664-224227 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 45 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=82913815&loc=SL49130534-203044 + Details
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- Definition The cash outflow for debt initially having maturity due after one year or beyond the normal operating cycle, if longer. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=109223946&loc=d3e3291-108585 + Details
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- Definition The amount of the write-off for research and development assets that were acquired in a transaction other than a business combination. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16265-109275 + Details
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