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Liquidity (Details)
1 Months Ended 3 Months Ended 4 Months Ended 6 Months Ended 9 Months Ended
Aug. 05, 2019
$ / shares
Apr. 25, 2019
USD ($)
Apr. 24, 2019
USD ($)
Sep. 21, 2018
USD ($)
Aug. 28, 2018
$ / shares
Jul. 25, 2018
USD ($)
$ / shares
shares
Jun. 01, 2018
USD ($)
May 23, 2018
$ / shares
shares
Oct. 31, 2019
USD ($)
shares
Sep. 30, 2019
USD ($)
$ / shares
shares
Aug. 31, 2019
$ / shares
shares
Sep. 30, 2019
USD ($)
$ / shares
shares
Jun. 30, 2019
USD ($)
shares
Mar. 31, 2019
USD ($)
shares
Sep. 30, 2018
USD ($)
shares
Jun. 30, 2018
USD ($)
shares
Mar. 31, 2018
USD ($)
shares
Dec. 31, 2018
USD ($)
$ / shares
shares
Jun. 30, 2019
USD ($)
Sep. 30, 2019
USD ($)
$ / shares
shares
Sep. 30, 2018
USD ($)
Aug. 16, 2019
shares
May 24, 2018
shares
Dec. 31, 2017
USD ($)
Liquidity [Line Items]                                                
Income (loss) from continuing operations                       $ 526,000     $ (1,396,000)         $ (4,203,000) $ (6,868,000)      
Accumulated deficit                   $ (426,154,000)   $ (426,154,000)           $ (414,383,000)   $ (426,154,000)        
Substantial doubt about going concern, description                                       These factors raise substantial doubt about our ability to continue as a going concern.        
Common stock issued (in shares) | shares           6,723                                    
Common stock, par value (in dollars per share) | $ / shares $ 0.001             $ 0.001   $ 0.001   $ 0.001           $ 0.001   $ 0.001        
Number of shares callable by warrants (in shares) | shares               23,400,000   50   50               50     2,300,000  
Exercise of warrants | shares                       490                        
Proceeds from offering                   $ 13,200,000                            
Cash proceeds from sale of subsidiary                                       $ 2,789,000 0      
Proceeds from sale of common stock, net                                       15,964,000 6,246,000      
Proceeds from issuance warrants           $ 5,700,000                           491,000 0      
Reverse stock split of common stock 0.02             0.1                                
Stockholders' equity (deficit)                   160,000   $ 160,000 $ (6,276,000) $ 3,857,000 6,138,000 $ 4,751,000 $ 8,480,000 $ 5,225,000 $ (6,276,000) 160,000 $ 6,138,000     $ 13,000,000
Common stock issued, value                         64,000 $ 1,873,000 $ 3,686,000 $ (297,000) $ 27,000              
Nasdaq Stock Market LLC [Member]                                                
Liquidity [Line Items]                                                
Reverse stock split of common stock                     0.02                          
Number of consecutive business days no longer able to meet the required closing bid price of common stock         30 days                                      
Minimum bid price of common stock required for Nasdaq listing rule | $ / shares         $ 1.00           $ 1.00                          
Grace period provided with minimum bid price for Nasdaq listing rule         180 days                                      
Grace date for minimum bid price requirement for Nasdaq listing         Feb. 25, 2019                                      
Common stock minimum bid price required to regain compliance | $ / shares         $ 1.00                                      
Number of consecutive business days required to regain compliance         10 days                                      
Date to regain compliance after meeting continued listing requirement         Aug. 26, 2019                                      
Additional grace period provided with minimum bid price to regain compliance         180 days                                      
Stockholders' equity (deficit)                   (160,000,000)   (160,000,000) $ 6,300,000           $ 6,300,000 (160,000,000)        
Minimum stockholders equity requirement                   $ 2,500,000   $ 2,500,000               $ 2,500,000        
Minimum shares requirement for continued listing | shares                                           500,000    
Description of compliance with minimum bid price requirement                                     We were also granted an additional compliance period of 180 calendar days, or until August 26, 2019, in which to regain compliance after meeting the continued listing requirement for market value of publicly held shares and all other initial listing standards for the Nasdaq Capital Market, with the exception of the bid price requirement, and providing notice to Nasdaq staff of our intent to cure the deficiency during this second compliance period, by effecting a reverse stock split, if necessary.          
Shares, Outstanding | shares                     786,807                          
UK Subsidiary and Cell Therapy Assets [Member]                                                
Liquidity [Line Items]                                                
Cash proceeds from sale of subsidiary     $ 3,400,000                                          
Japanese Subsidiary and Cell Therapy Assets [Member]                                                
Liquidity [Line Items]                                                
Cash proceeds from sale of subsidiary   $ 2,500,000                                            
Series U Warrants [Member]                                                
Liquidity [Line Items]                                                
Common stock issued (in shares) | shares                                       3,450,000        
Sale of Stock, Price Per Share | $ / shares                   $ 5.00   $ 5.00               $ 5.00        
Series U Warrants [Member]                                                
Liquidity [Line Items]                                                
Number of shares callable by warrants (in shares) | shares                   75,000   75,000               75,000        
Warrant exercise price | $ / shares                   $ 6.25   $ 6.25               $ 6.25        
Common Stock [Member]                                                
Liquidity [Line Items]                                                
Common stock issued (in shares) | shares           6,723             5,000 139,855 29,407 192 202              
Number of shares callable by warrants (in shares) | shares           141,183                                    
Exercise of warrants | shares                 1,039,000                     1,672,000        
Warrant exercise price | $ / shares           $ 39.93                                    
Stockholders' equity (deficit)                   $ 3,000   $ 3,000               $ 3,000        
Common Stock [Member] | B. Riley FBR [Member] | Sales Agreement [Member]                                                
Liquidity [Line Items]                                                
Remaining availability under financing facility                   $ 0   $ 0               $ 0        
Common Stock [Member] | Lincoln Park [Member]                                                
Liquidity [Line Items]                                                
Common stock issued (in shares) | shares                                   12,802   32,170        
Proceeds from sale of common stock, net                                   $ 300,000   $ 300,000        
Common stock issued, value       $ 5,000,000                                        
Period exercisable from the date of issuance       24 months                                        
Common Stock [Member] | Maximum [Member] | B. Riley FBR [Member] | Sales Agreement [Member]                                                
Liquidity [Line Items]                                                
Proceeds from sale of common stock, net             $ 6,500,000                                  
Common Stock [Member] | Maximum [Member] | Lincoln Park [Member]                                                
Liquidity [Line Items]                                                
Remaining availability under financing facility       $ 100,000                                        
Common Class A [Member]                                                
Liquidity [Line Items]                                                
Common stock issued (in shares) | shares                                       289,000        
Common Class B [Member]                                                
Liquidity [Line Items]                                                
Number of shares callable by warrants (in shares) | shares                   2,711,000   2,711,000               2,711,000        
Series C Convertible Preferred Stock [Member]                                                
Liquidity [Line Items]                                                
Number of shares callable by warrants (in shares) | shares           7,059,150                                    
Number of convertible shares converted into common stock (in shares) | shares           200,000                                    
Series C Convertible Preferred Stock [Member] | Common Stock [Member]                                                
Liquidity [Line Items]                                                
Number of convertible shares converted into common stock (in shares) | shares                           1,653                    
Underwriter                                                
Liquidity [Line Items]                                                
Underwritten public offering description                   pursuant to which the Company sold in an underwritten public offering an aggregate of (i) 289,000 Class A Units, each consisting of one share of common stock, par value $0.001 per share, of the Company and one Series U Warrant to purchase one share of Common stock, and (ii) 2,711,000 Class B Units, each consisting of one pre-funded Series V Warrant to purchase one share of Common stock and one Series U Warrant to purchase one share of Common stock at a public offering price of $5.00 per Class A Unit and $4.9999 per Class B Unit (“September 2019 Offering”). In addition, the Company granted the Underwriters a 45-day option to purchase up to an additional 450,000 shares of the Company’s Common stock and/or Series U Warrants at the public offering price, less the underwriting discounts and commissions. The Underwriters exercised their option to purchase an additional 450,000 Series U Warrants. The Company also issued to the Representative warrants (in the form of the Series U Warrants) to purchase 75,000 shares of common stock with an exercise price of $6.25 per share of common stock (“Representative Warrants”).                            
Option vesting period                   45 days                            
Warrant granted | shares                   450,000                            
Underwriter | Maximum [Member]                                                
Liquidity [Line Items]                                                
Option granted | shares                   450,000                            
Underwriter | Series U Warrants [Member]                                                
Liquidity [Line Items]                                                
Exercise of warrants | shares                   450,000                            
Underwriter | Series U Warrants [Member]                                                
Liquidity [Line Items]                                                
Number of shares callable by warrants (in shares) | shares                   75,000   75,000               75,000        
Warrant exercise price | $ / shares                   $ 6.25   $ 6.25               $ 6.25        
Underwriter | Common Class A [Member]                                                
Liquidity [Line Items]                                                
Common stock issued (in shares) | shares                   289,000                            
Common stock, par value (in dollars per share) | $ / shares                   $ 0.001   0.001               0.001        
Underwriter | Common Class A [Member] | Series U Warrants [Member]                                                
Liquidity [Line Items]                                                
Sale of Stock, Price Per Share | $ / shares                   $ 5.00   $ 5.00               $ 5.00        
Underwriter | Common Class B [Member] | Series V Warrants                                                
Liquidity [Line Items]                                                
Number of shares callable by warrants (in shares) | shares                   2,711,000   2,711,000               2,711,000        
Underwriter | Common Class B [Member] | Series U Warrants [Member]                                                
Liquidity [Line Items]                                                
Sale of Stock, Price Per Share | $ / shares                   $ 4.9999   $ 4.9999               $ 4.9999        
Subsequent Event                                                
Liquidity [Line Items]                                                
Revenue received in cash                 $ 4,600,000                              
Subsequent Event | Barda Contract [Member]                                                
Liquidity [Line Items]                                                
Revenue received in cash                 $ 4,600,000                              
B A R D A Agreement                                                
Liquidity [Line Items]                                                
Income (loss) from continuing operations                       $ 526,000               $ (4,200,000)        
Revenue recognized                       $ 4,600,000                        
Amendment to Loan and Security Agreement [Member] | UK Subsidiary and Cell Therapy Assets [Member]                                                
Liquidity [Line Items]                                                
Payments for principal, interest and fees     $ 1,700,000                                          
Amendment to Loan and Security Agreement [Member] | Japanese Subsidiary and Cell Therapy Assets [Member]                                                
Liquidity [Line Items]                                                
Payments for principal, interest and fees   $ 1,400,000