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Stockholders' Equity - Preferred Stock (Details) - USD ($)
 3 Months Ended 12 Months Ended
Jul. 25, 2018
Jul. 17, 2018
Nov. 28, 2017
Nov. 02, 2017
Mar. 31, 2019
Mar. 31, 2018
Dec. 31, 2018
Dec. 31, 2017
May 24, 2018
May 23, 2018
Nov. 27, 2017
Preferred Stock [Abstract]                      
Preferred stock, shares authorized (in shares)         5,000,000   5,000,000 5,000,000 5,000,000 5,000,000  
Preferred stock, par value (in dollars per share)         $ 0.001   $ 0.001 $ 0.001      
Preferred stock, shares issued (in shares)         30,223   30,223 30,223      
Preferred stock, shares outstanding (in shares)         4,540   4,606 2,431      
Number of shares callable by warrants (in shares)                 2,300,000 23,400,000  
Common stock issued (in shares) 6,723   10,000                
Common Stock [Member]                      
Preferred Stock [Abstract]                      
Number of shares callable by warrants (in shares) 50   36,000                
Warrant exercise price (in dollars per share) $ 39.93   $ 166.65                
Common stock issued (in shares) 6,723   10,000   139,855 201 92,169 24,474      
2017 Rights Offering [Member]                      
Preferred Stock [Abstract]                      
Charge on Non Transferable Subscription Rights       $ 0              
Number of shares callable by warrants (in shares)       10,000              
Warrant exercise price (in dollars per share)       $ 3.333              
Period exercisable from the date of issuance             30 months        
Common stock issued (in shares)     10,000                
Gross proceeds from private placement of stock     $ 8,800,000                
Redemption price of warrant prior to expiration             $ 0.01        
Common stock price per share for warrant redemption             $ 8.33        
Number of consecutive trading days for warrant redemption             10 days        
2017 Rights Offering [Member] | Outstanding Warrants [Member]                      
Preferred Stock [Abstract]                      
Number of shares callable by warrants (in shares)       18,000,000              
Number of warrants exercisable       10              
2017 Rights Offering [Member] | Common Stock [Member]                      
Preferred Stock [Abstract]                      
Number of shares callable by warrants (in shares)       1              
2018 Rights Offering [Member]                      
Preferred Stock [Abstract]                      
Number of shares callable by warrants (in shares)   1                  
Warrant exercise price (in dollars per share)   $ 39.93                  
Period exercisable from the date of issuance         30 months   30 months        
Common stock issued (in shares) 6,723                    
Gross proceeds from private placement of stock $ 5,700,000                    
Redemption price of warrant prior to expiration         $ 0.50   $ 0.50        
Common stock price per share for warrant redemption         $ 181.50   $ 181.50        
Number of consecutive trading days for warrant redemption         20 days   20 days        
Warrants liability fair value $ 3,100,000       $ 1,500,000   $ 900,000        
2018 Rights Offering [Member] | Outstanding Warrants [Member]                      
Preferred Stock [Abstract]                      
Number of shares callable by warrants (in shares)   1,050                  
Warrant exercise price (in dollars per share)   $ 1,000                  
2018 Rights Offering [Member] | Common Stock [Member]                      
Preferred Stock [Abstract]                      
Number of shares callable by warrants (in shares) 141,183 141,183                  
Series A Convertible Preferred Stock [Member]                      
Preferred Stock [Abstract]                      
Preferred stock, shares issued (in shares)         13,500   13,500 13,500      
Convertible preferred stock         3.60%   3.60% 3.60%      
Preferred stock, shares outstanding (in shares)         0   0 0      
Series B Convertible Preferred Stock [Member]                      
Preferred Stock [Abstract]                      
Preferred stock, shares authorized (in shares)                     10,000
Preferred stock, par value (in dollars per share)                     $ 0.001
Preferred stock, shares issued (in shares)         10,000   10,000 10,000      
Preferred stock, shares outstanding (in shares)         1,112   1,112 2,431      
Number of shares callable by warrants (in shares)     360,000                
Common stock issued (in shares)     60,000                
Series B Convertible Preferred Stock [Member] | 2017 Rights Offering [Member]                      
Preferred Stock [Abstract]                      
Number of shares callable by warrants (in shares)       10,000              
Series C Convertible Preferred Stock [Member]                      
Preferred Stock [Abstract]                      
Preferred stock, shares authorized (in shares) 7,000                    
Preferred stock, par value (in dollars per share) $ 0.001                    
Preferred stock, shares issued (in shares)         6,723   6,723        
Preferred stock, shares outstanding (in shares)         3,428   3,494 0      
Number of shares callable by warrants (in shares) 7,059,150                    
Number of share converted into common stock for each share (in shares) 25                    
Series C Convertible Preferred Stock [Member] | Dividend Paid [Member]                      
Preferred Stock [Abstract]                      
Dividends payable             $ 2,500,000        
Series C Convertible Preferred Stock [Member] | 2018 Rights Offering [Member]                      
Preferred Stock [Abstract]                      
Number of shares callable by warrants (in shares)   20,000                  
Common Stock and Series B Convertible Preferred Stock [Member] | 2018 Rights Offering [Member]                      
Preferred Stock [Abstract]                      
Charge on Non Transferable Subscription Rights   $ 0