<SEC-DOCUMENT>0001564590-20-046208-index.html : 20201009
<SEC-HEADER>0001564590-20-046208.hdr.sgml : 20201009
<ACCEPTANCE-DATETIME>20201009161001
ACCESSION NUMBER:		0001564590-20-046208
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20201009
DATE AS OF CHANGE:		20201009

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PLUS THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001095981
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				330827593
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-249410
		FILM NUMBER:		201233312

	BUSINESS ADDRESS:	
		STREET 1:		4200 MARATHON BLVD.
		STREET 2:		SUITE 200
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78756
		BUSINESS PHONE:		737.255.7194

	MAIL ADDRESS:	
		STREET 1:		4200 MARATHON BLVD.
		STREET 2:		SUITE 200
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78756

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTORI THERAPEUTICS, INC.
		DATE OF NAME CHANGE:	20050712

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MACROPORE INC
		DATE OF NAME CHANGE:	20010320
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>pstv-s3.htm
<DESCRIPTION>S-3
<TEXT>
Document 1 - file: pstv-s3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.1
<SEQUENCE>2
<FILENAME>pstv-ex41_6.htm
<DESCRIPTION>EX-4.1
<TEXT>
Document 2 - file: pstv-ex41_6.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>pstv-ex51_7.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 3 - file: pstv-ex51_7.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>4
<FILENAME>pstv-ex232_8.htm
<DESCRIPTION>EX-23.2
<TEXT>
Document 4 - file: pstv-ex232_8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>g4qqtzfd0tbf000001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: g4qqtzfd0tbf000001.jpg

</DOCUMENT>
</SEC-DOCUMENT>