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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019
Cash flows used in operating activities: |  |
Net loss | $ (8,241) | $ (10,887)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 366 | 896
Amortization of deferred financing costs and debt discount | 584 | 550
In process research and development acquired from NanoTx Therapeutics | 781 | 0
Change in fair value of liability instruments | (2,400) | (3,407)
Share-based compensation expense | 247 | 127
Inventory write off | 107 | 0
Noncash lease expense | 3 | 12
Loss on sale of business | 0 | 6,508
Allocation of issuance cost associated with warrants | 0 | 1,233
Increases (decreases) in cash caused by changes in operating assets and liabilities: |  |
Accounts receivable | 1,169 | (1,203)
Inventories | 0 | 259
Other current assets | 126 | (211)
Other assets | 58 | 263
Accounts payable and accrued expenses | (1,234) | (28)
Deferred revenue | 0 | 29
Other long-term liabilities | 0 | (47)
Net cash used in operating activities | (8,434) | (5,906)
Cash flows from (used in) investing activities: |  |
Purchases of property and equipment and intangible assets | (93) | (67)
In process research and development acquired from NanoTx Therapeutics | (400) | 0
Proceeds from sale of business | 0 | 5,637
Net cash provided by (used in) investing activities | (493) | 5,570
Cash flows from financing activities: |  |
Principal payments of long-term obligations | (5,307) | (3,692)
Payment of financing lease liability | (117) | (131)
Proceeds from exercise of warrants | 1,098 | 490
Proceeds from sale of common stock | 4,007 | 15,964
Net cash (used in) provided by financing activities | (319) | 12,631
Effect of exchange rate changes on cash and cash equivalents | 0 | (4)
Net increase (decrease) in cash and cash equivalents | (9,246) | 12,291
Cash, cash equivalents, and restricted cash at beginning of period | 17,592 | 5,301
Cash, cash equivalents, and restricted cash at end of period | 8,346 | 17,592
Cash paid during period for: |  |
Interest | 567 | 1,188
Supplemental schedule of non-cash investing and financing activities: |  |
Issuance costs paid in common stock | 463 | 0
Common stock issued in payment for in process research and development | 381 | 0
Unpaid offering cost | 125 | 0
Reclassification of warrants liability to equity | 4,504 | 794
Proceeds from sales of business, net, paid directly to lender for principal payment of long-term obligations | 0 | 3,050
Offering cost paid in warrants | 0 | 213
Fair value of Convertible Preferred Stock beneficial conversion feature | $ 0 | $ 554

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