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Income Taxes - Reconciliation of Total Income Tax Provision (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Reconciliation of the total income tax provision tax rate [Abstract]    
Income tax expense (benefit) at federal statutory rate (21.00%) (21.00%)
Change in valuation allowance 0.90% 23.60%
Income tax expense (benefit) at state statutory rate (0.60%) (8.90%)
Stock compensation 0.70% 6.90%
NOLs expiring and adjustments to NOL 20.30% 6.00%
Research credit (0.80%) (1.10%)
Return to provision 0.50% 1.00%
Change in state rate   (0.50%)
Mark to market adjustment   (6.10%)
Other, net   0.10%
Total income tax provision 0.00% 0.00%