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Commitments and Contingencies - Additional Information (Details) - USD ($)
3 Months Ended
Mar. 31, 2022
Jun. 22, 2021
Mar. 01, 2021
Jan. 08, 2021
Mar. 31, 2022
Mar. 31, 2021
Recorded Unconditional Purchase Obligation [Line Items]            
Operating leases expiry year         2025  
Minimum lease payment $ 382,000       $ 382,000  
Operating lease, weighted average discount rate 9.00%       9.00%  
Operating lease, weighted average remaining term 2 years 9 months 25 days       2 years 9 months 25 days  
Rent expense         $ 60,000 $ 50,000
Lorem Vascular Pte Ltd [Member]            
Recorded Unconditional Purchase Obligation [Line Items]            
Compensatory damages and operational   $ 6,000,000        
Pre-clinical Research Study Obligations [Member]            
Recorded Unconditional Purchase Obligation [Line Items]            
Contractual obligation $ 0       0  
Pre-clinical Research Study Obligations [Member] | Lorem Vascular Pte Ltd [Member]            
Recorded Unconditional Purchase Obligation [Line Items]            
Litigation settlement, expense         0  
Charlottesville [Member]            
Recorded Unconditional Purchase Obligation [Line Items]            
Lessee, operating lease, term of contract     12 months      
Lessee, operating lease, existence of option to extend [true false]     true      
Lessee, operating lease, option to extend     The Charlottesville Lease has a term of 12 months and is renewable for four additional one-year periods.      
Lessee, operating lease, renewal term     1 year      
Minimum lease payment     $ 30,000      
Annual increase in lease rate     3.00%      
Lease commencement date     Apr. 01, 2021      
Operating leases, expiration date     Mar. 31, 2023      
Medidata Solutions, Inc. [Member] | Services Agreement [Member]            
Recorded Unconditional Purchase Obligation [Line Items]            
Statement of work, term 6 months          
Managed services fees payable $ 1,450,000       1,450,000  
Contingent managed services fee $ 150,000       $ 150,000  
Piramal Pharma Solutions, Inc. [Member]            
Recorded Unconditional Purchase Obligation [Line Items]            
Master service agreement date       Jan. 08, 2021    
Master services agreement initial term       5 years    
Master services agreement terms, Description         The MSA has a term of five years and will automatically renew for successive one-year terms unless either party notifies the other no later than six months prior to the original term or any additional terms of its intention to not renew the MSA.  The Company has the right to terminate the MSA for convenience upon thirty days’ prior written notice.