<SEC-DOCUMENT>0001564590-22-013877-index.html : 20220407
<SEC-HEADER>0001564590-22-013877.hdr.sgml : 20220407
<ACCEPTANCE-DATETIME>20220407170056
ACCESSION NUMBER:		0001564590-22-013877
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		7
CONFORMED PERIOD OF REPORT:	20220516
FILED AS OF DATE:		20220407
DATE AS OF CHANGE:		20220407

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PLUS THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001095981
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				330827593
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34375
		FILM NUMBER:		22814546

	BUSINESS ADDRESS:	
		STREET 1:		4200 MARATHON BLVD.
		STREET 2:		SUITE 200
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78756
		BUSINESS PHONE:		737.255.7194

	MAIL ADDRESS:	
		STREET 1:		4200 MARATHON BLVD.
		STREET 2:		SUITE 200
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78756

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTORI THERAPEUTICS, INC.
		DATE OF NAME CHANGE:	20050712

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MACROPORE INC
		DATE OF NAME CHANGE:	20010320
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>pstv-def14a_20220516.htm
<DESCRIPTION>DEF 14A
<TEXT>
Document 1 - file: pstv-def14a_20220516.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>gdtdc5zscevp000005.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: gdtdc5zscevp000005.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>gdtdc5zscevp000002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: gdtdc5zscevp000002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>gdtdc5zscevp000006.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: gdtdc5zscevp000006.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>gdtdc5zscevp000001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: gdtdc5zscevp000001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>gdtdc5zscevp000004.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: gdtdc5zscevp000004.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>gdtdc5zscevp000007.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: gdtdc5zscevp000007.jpg

</DOCUMENT>
</SEC-DOCUMENT>