<SEC-DOCUMENT>0001193125-22-215328-index.html : 20220809
<SEC-HEADER>0001193125-22-215328.hdr.sgml : 20220809
<ACCEPTANCE-DATETIME>20220808214643
ACCESSION NUMBER:		0001193125-22-215328
CONFORMED SUBMISSION TYPE:	S-1
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20220809
DATE AS OF CHANGE:		20220808

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PLUS THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001095981
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				330827593
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-266684
		FILM NUMBER:		221146178

	BUSINESS ADDRESS:	
		STREET 1:		4200 MARATHON BLVD.
		STREET 2:		SUITE 200
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78756
		BUSINESS PHONE:		737.255.7194

	MAIL ADDRESS:	
		STREET 1:		4200 MARATHON BLVD.
		STREET 2:		SUITE 200
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78756

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTORI THERAPEUTICS, INC.
		DATE OF NAME CHANGE:	20050712

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MACROPORE INC
		DATE OF NAME CHANGE:	20010320
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1
<SEQUENCE>1
<FILENAME>d323487ds1.htm
<DESCRIPTION>S-1
<TEXT>
Document 1 - file: d323487ds1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>d323487dex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: d323487dex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>d323487dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 3 - file: d323487dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>d323487dexfilingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 4 - file: d323487dexfilingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>g323487dsp46.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: g323487dsp46.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>g323487g01a00.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: g323487g01a00.jpg

</DOCUMENT>
</SEC-DOCUMENT>