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Income Taxes - Reconciliation of Total Income Tax Provision (Details)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Reconciliation of the total income tax provision tax rate [Abstract]    
Income tax expense (benefit) at federal statutory rate (21.00%) (21.00%)
Change in valuation allowance 22.50% (699.50%)
Income tax expense (benefit) at state statutory rate (0.20%) (0.60%)
Share based compensation 0.90% 0.70%
NOLs expiring and adjustments to NOL 0.50% 720.70%
Research credit (2.50%) (0.80%)
Return to provision (0.10%) 0.50%
Change in state rate (0.10%)  
Total income tax provision 0.00% (0.00%)