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STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Cash flows used in operating activities:    
Net loss $ (20,275) $ (13,399)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 619 395
Amortization of deferred financing costs and debt discount 389 546
In process research and development acquired 0 250
Change in fair value of liability instruments (1) (6)
Loss on disposal of property and equipment 0 66
Share-based compensation expense 606 606
Amortization of operating lease right-of-use assets 93 24
Increases (decreases) in cash caused by changes in operating assets and liabilities:    
Other current assets (2,369) (496)
Accounts payable and accrued expenses 6,452 1,734
Change in operating lease liabilities (129)  
Other long-term liabilities 1,643 0
Net cash used in operating activities (12,972) (10,280)
Cash flows from (used in) investing activities:    
Purchases of property and equipment and intangible assets (509) (144)
In process research and development acquired (250) 0
Proceeds from sale of property and equipment 0 62
Net cash used in investing activities (759) (82)
Cash flows from financing activities:    
Principal payments of long-term obligations (1,608) (268)
Payment of finance lease liability 0 (8)
Proceeds from exercise of warrants 0 2,017
Proceeds from sale of common stock 15,059 18,675
Net cash provided by financing activities 13,451 20,416
Net increase (decrease) in cash and cash equivalents (280) 10,054
Cash and cash equivalents at beginning of period 18,400 8,346
Cash and cash equivalents at end of period 18,120 18,400
Cash paid during period for:    
Interest 327 388
Supplemental schedule of non-cash investing and financing activities:    
Unpaid offering cost $ 0 $ 219