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Commitments and Contingencies - Additional Information (Details) - USD ($)
3 Months Ended
Mar. 31, 2022
Jun. 22, 2021
Jan. 08, 2021
Mar. 31, 2023
Mar. 31, 2022
Recorded Unconditional Purchase Obligation [Line Items]          
Operating leases expiry year       2025  
Lease liability       $ 273,000  
Operating lease, weighted average discount rate       9.00%  
Operating lease, weighted average remaining term       2 years 3 months 7 days  
Rent expense       $ 47,000 $ 60,000
Lorem Vascular Pte Ltd [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Compensatory damages and operational   $ 6,000,000      
Litigation settlement, expense       1,400,000  
Pre-clinical Research Study Obligations [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Contractual obligation       $ 0  
Charlottesville [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Lessee, operating lease, term of contract       12 months  
Lessee, operating lease, existence of option to extend [true false]       true  
Lessee, operating lease, option to extend       The Charlottesville Lease has a term of 12 months and the Company has the ability to renew for three additional one-year periods.  
Lessee, operating lease, renewal term       1 year  
Operating leases, expiration date       Mar. 31, 2024  
Lease liability       $ 80,000  
Operating lease discount rate       12.76%  
Medidata Solutions, Inc. [Member] | Services Agreement [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Sales order term 6 months        
Piramal Pharma Solutions, Inc. [Member]          
Recorded Unconditional Purchase Obligation [Line Items]          
Master service agreement date     Jan. 08, 2021    
Master services agreement initial term     5 years    
Master services agreement terms, Description       The MSA has a term of five years and will automatically renew for successive one-year terms unless either party notifies the other no later than six months prior to the original term or any additional terms of its intention to not renew the MSA. The Company has the right to terminate the MSA for convenience upon thirty days’ prior written notice.