<SEC-DOCUMENT>0001193125-25-142215-index.html : 20250618
<SEC-HEADER>0001193125-25-142215.hdr.sgml : 20250618
<ACCEPTANCE-DATETIME>20250617212153
ACCESSION NUMBER:		0001193125-25-142215
CONFORMED SUBMISSION TYPE:	S-1
PUBLIC DOCUMENT COUNT:		9
FILED AS OF DATE:		20250618
DATE AS OF CHANGE:		20250617

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PLUS THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001095981
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		ORGANIZATION NAME:           	08 Industrial Applications and Services
		EIN:				330827593
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-288121
		FILM NUMBER:		251054973

	BUSINESS ADDRESS:	
		STREET 1:		4200 MARATHON BLVD.
		STREET 2:		SUITE 200
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78756
		BUSINESS PHONE:		737.255.7194

	MAIL ADDRESS:	
		STREET 1:		4200 MARATHON BLVD.
		STREET 2:		SUITE 200
		CITY:			AUSTIN
		STATE:			TX
		ZIP:			78756

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CYTORI THERAPEUTICS, INC.
		DATE OF NAME CHANGE:	20050712

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MACROPORE INC
		DATE OF NAME CHANGE:	20010320
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1
<SEQUENCE>1
<FILENAME>d908161ds1.htm
<DESCRIPTION>S-1
<TEXT>
Document 1 - file: d908161ds1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>d908161dex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: d908161dex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.38
<SEQUENCE>3
<FILENAME>d908161dex1038.htm
<DESCRIPTION>EX-10.38
<TEXT>
Document 3 - file: d908161dex1038.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-10.39
<SEQUENCE>4
<FILENAME>d908161dex1039.htm
<DESCRIPTION>EX-10.39
<TEXT>
Document 4 - file: d908161dex1039.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>5
<FILENAME>d908161dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 5 - file: d908161dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>6
<FILENAME>d908161dexfilingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 6 - file: d908161dexfilingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>g908161g03n35.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: g908161g03n35.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>g908161img02.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: g908161img02.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>g908161img04.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: g908161img04.jpg

</DOCUMENT>
</SEC-DOCUMENT>