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Document and Entity Information
Aug. 07, 2025
Cover [Abstract]  
Document Type 8-K
Document Period End Date Aug. 07, 2025
Entity Registrant Name PLUS THERAPEUTICS, INC.
Entity Incorporation State Country Code DE
Entity File Number 001-34375
Entity Tax Identification Number 33-0827593
Entity Address Address Line 1 2710 Reed Road
Entity Address Address Line 2 Suite 160
Entity Address City Or Town Houston
Entity Address State Or Province TX
Entity Address Postal Zip Code 77051
City Area Code 737
Local Phone Number 255-7194
Written Communications false
Soliciting Material false
Pre Commencement Tender Offer false
Pre Commencement Issuer Tender Offer false
Security 12b Title Common Stock, par value $0.001
Trading Symbol PSTV
Security Exchange Name NASDAQ
Entity Emerging Growth Company false
Entity Central Index Key 0001095981
Amendment Flag false