<SEC-DOCUMENT>0001209191-18-052851.txt : 20181001
<SEC-HEADER>0001209191-18-052851.hdr.sgml : 20181001
<ACCEPTANCE-DATETIME>20181001172838
ACCESSION NUMBER:		0001209191-18-052851
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20180927
FILED AS OF DATE:		20181001
DATE AS OF CHANGE:		20181001

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SVLSF V, LLC
		CENTRAL INDEX KEY:			0001644160
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38662
		FILM NUMBER:		181098594

	BUSINESS ADDRESS:	
		STREET 1:		C/O SV LIFE SCIENCES ADVISERS, LLC
		STREET 2:		ONE BOSTON PLACE, SUITE 3900
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		617-367-8100

	MAIL ADDRESS:	
		STREET 1:		C/O SV LIFE SCIENCES ADVISERS, LLC
		STREET 2:		ONE BOSTON PLACE, SUITE 3900
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			ILSF III, LLC
		CENTRAL INDEX KEY:			0001630791
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38662
		FILM NUMBER:		181098595

	BUSINESS ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		(617) 367-8100

	MAIL ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			INTERNATIONAL LIFE SCIENCES FUND III (GP), L.P.
		CENTRAL INDEX KEY:			0001630790
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38662
		FILM NUMBER:		181098596

	BUSINESS ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		(617) 367-8100

	MAIL ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			INTERNATIONAL LIFE SCIENCES FUND III STRATEGIC PARTNERS, L.P.
		CENTRAL INDEX KEY:			0001233226

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38662
		FILM NUMBER:		181098597

	BUSINESS ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		617-367-8100

	MAIL ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108

	FORMER NAME:	
		FORMER CONFORMED NAME:	INTERNATIONAL LIFE SCIENCES FUND III STRATEGIC PARTNERS L P
		DATE OF NAME CHANGE:	20030515

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			INTERNATIONAL LIFE SCIENCES FUND III CO-INVESTMENT, L.P.
		CENTRAL INDEX KEY:			0001233315

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38662
		FILM NUMBER:		181098598

	BUSINESS ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		617-367-8100

	MAIL ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108

	FORMER NAME:	
		FORMER CONFORMED NAME:	INTERNATIONAL LIFE SCIENCES FUND III CO INVESTMENT L P
		DATE OF NAME CHANGE:	20030515

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			INTERNATIONAL LIFE SCIENCES FUND III (LP1), L.P.
		CENTRAL INDEX KEY:			0001172861

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38662
		FILM NUMBER:		181098599

	BUSINESS ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		6173671590

	MAIL ADDRESS:	
		STREET 1:		ONE BOSTON PLACE, SUITE 3900
		STREET 2:		201 WASHINGTON STREET
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108

	FORMER NAME:	
		FORMER CONFORMED NAME:	INTERNATIONAL LIFE SCIENCES FUND III LP1 LP
		DATE OF NAME CHANGE:	20020508

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SV Life Sciences Fund V (GP), LP
		CENTRAL INDEX KEY:			0001644146
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38662
		FILM NUMBER:		181098600

	BUSINESS ADDRESS:	
		STREET 1:		C/O SV LIFE SCIENCES ADVISERS, LLC
		STREET 2:		ONE BOSTON PLACE, SUITE 3900
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		617-367-8100

	MAIL ADDRESS:	
		STREET 1:		C/O SV LIFE SCIENCES ADVISERS, LLC
		STREET 2:		ONE BOSTON PLACE, SUITE 3900
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SV LIFE SCIENCES FUND V LP
		CENTRAL INDEX KEY:			0001460732
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38662
		FILM NUMBER:		181098601

	BUSINESS ADDRESS:	
		STREET 1:		C/O SV LIFE SCIENCES ADVISERS, LLC
		STREET 2:		ONE BOSTON PLACE, SUITE 3900
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		617-973-2708

	MAIL ADDRESS:	
		STREET 1:		C/O SV LIFE SCIENCES ADVISERS, LLC
		STREET 2:		ONE BOSTON PLACE, SUITE 3900
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SV Life Sciences Fund V Strategic Partners, L.P.
		CENTRAL INDEX KEY:			0001482194
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38662
		FILM NUMBER:		181098602

	BUSINESS ADDRESS:	
		STREET 1:		C/O SV LIFE SCIENCES ADVISERS, LLC
		STREET 2:		ONE BOSTON PLACE, SUITE 3900
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		617-973-2708

	MAIL ADDRESS:	
		STREET 1:		C/O SV LIFE SCIENCES ADVISERS, LLC
		STREET 2:		ONE BOSTON PLACE, SUITE 3900
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			SUTRO BIOPHARMA INC
		CENTRAL INDEX KEY:			0001382101
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				452441988
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		310 UTAH AVE., SUITE 150
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		650-392-8412

	MAIL ADDRESS:	
		STREET 1:		310 UTAH AVE., SUITE 150
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
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    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2018-10-01</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
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                <transactionCode>C</transactionCode>
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            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
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        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
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        </nonDerivativeTransaction>
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                    <value>By SV Life Sciences Fund V Strategic Partners, L.P.</value>
                    <footnoteId id="F8"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Series E Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F7"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2018-10-01</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>193492</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F7"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F7"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>5320</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By SV Life Sciences Fund V Strategic Partners, L.P.</value>
                    <footnoteId id="F8"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Each share of the issuer's Series A Preferred Stock automatically converted into 0.0433 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its firm commitment initial public offering (the &quot;IPO&quot;) pursuant to a registration statement on Form S-1 (File No. 333-227103) under the Securities Act of 1933, as amended (the &quot;Registration Statement&quot;), and had no expiration date.</footnote>
        <footnote id="F2">International Life Sciences Fund III (GP), LP. (&quot;Fund III GP&quot;) is the general partner of each of: (i) International Life Sciences Fund III (LP1), L.P. (&quot;ILSF LP1&quot;), (ii) International Life Sciences Fund III Co-Investment, L.P. (&quot;ILSF Co-Invest&quot;) and (iii) International Life Sciences Fund III Strategic Partners, L.P. (&quot;ILSF Strategic&quot; and collectively, the &quot;Fund III Entities&quot;). ILSF III, LLC (the &quot;ILSF General Partner&quot;) is the general partner of Fund III GP and, through an investment committee comprised of James Garvey, Kate Bingham, Eugene D. Hill, III and Michael J. Ross controls voting and investment decisions over the Issuer's shares held by the Fund III Entities by majority vote. Each of Fund III GP, ILSF General Partner, and each member of the investment committee of ILSF General Partner disclaims beneficial ownership over the Shares held by the Fund III Entities except to the extent of any pecuniary interest therein.</footnote>
        <footnote id="F3">Each share of the issuer's Series B Preferred Stock automatically converted into 0.0578 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date.</footnote>
        <footnote id="F4">Each share of the issuer's Series C Preferred Stock automatically converted into 0.0370 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date.</footnote>
        <footnote id="F5">These shares are owned directly by SV Life Sciences Fund V, L.P. (&quot;SVLS V LP&quot;). SV Life Sciences Fund V (GP), LP (&quot;SVLS V GP&quot;) is the general partner of SVLS V LP. The general partner of SVLS V GP is SVLSF V, LLC. Kate Bingham, James Garvey, Eugene D. Hill, III and Michael J. Ross are members of the investment committee of SVLSF V, LLC. SVLS V GP, SVLSF V, LLC and each of the individuals comprising the SVLSF V, LLC investment committee may be deemed to share voting, dispositive and investment power over the shares held of record by SVLS V LP. Each of SVLS V GP, SVLSF V, LLC and the individual members of the SVLSF V, LLC investment committee disclaims beneficial ownership of these securities and this report shall not be deemed to be an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or any other purpose, except to the extent of their pecuniary interest therein.</footnote>
        <footnote id="F6">Each share of the issuer's Series D Preferred Stock automatically converted into 0.0405 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date.</footnote>
        <footnote id="F7">Each share of the issuer's Series E Preferred Stock automatically converted into 0.0275 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date.</footnote>
        <footnote id="F8">These shares are owned directly by SV Life Sciences Fund V Strategic Partners, L.P. (&quot;SVLS V SPP&quot;). SVLS V GP is the general partner of SVLS V SPP. The general partner of SVLS V GP is SVLSF V, LLC. Kate Bingham, James Garvey, Eugene D. Hill, III and Michael J. Ross are members of the investment committee of SVLSF V, LLC. SVLS V GP, SVLSF V, LLC and each of the individuals comprising the SVLSF V, LLC investment committee may be deemed to share voting, dispositive and investment power over the shares held of record by SVLS V SPP. Each of SVLS V GP, SVLSF V, LLC and the individual members of the SVLSF V, LLC investment committee disclaims beneficial ownership of these securities and this report shall not be deemed to be an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or any other purpose, except to the extent of their pecuniary interest therein.</footnote>
        <footnote id="F9">The warrant is exercisable at any time at the holder's election on a one-for one basis and automatically terminates on the completion of the issuer's initial public offering if not earlier exercised.</footnote>
        <footnote id="F10">Each share of the issuer's Series C Preferred Stock will automatically convert into 0.0370 share of the issuer's Common Stock immediately upon the closing of the issuer's IPO and has no expiration date.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Brent Faduski as authorized officer of SVLSF V, LLC</signatureName>
        <signatureDate>2018-10-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brent Faduski as authorized officer of ILSF III, LLC</signatureName>
        <signatureDate>2018-10-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brent Faduski as authorized officer of ILSF III, LLC, the GP of International Life Sciences Fund III (GP), L.P.</signatureName>
        <signatureDate>2018-10-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brent Faduski as authorized officer of ILSF III, LLC, the GP of International Life Sciences Fund III (GP), L.P., the GP of International Life Sciences Fund III Strategic Partners, L.P.</signatureName>
        <signatureDate>2018-10-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brent Faduski as authorized officer of ILSF III, LLC, the GP of International Life Sciences Fund III (GP), L.P., the GP of International Life Sciences Fund III Co-Investment, L.P.</signatureName>
        <signatureDate>2018-10-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brent Faduski as authorized officer of ILSF III, LLC, the GP of International Life Sciences Fund III (GP), L.P., the GP of International Life Sciences Fund III (LP1), L.P.</signatureName>
        <signatureDate>2018-10-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brent Faduski as authorized officer of SVLSF V, LLC, the GP of SV Life Sciences Fund V (GP), L.P.</signatureName>
        <signatureDate>2018-10-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brent Faduski as authorized officer of SVLSF V, LLC, the GP of I SV Life Sciences Fund V (GP), L.P, L.P., the GP of SV Life Sciences Fund V, L.P.</signatureName>
        <signatureDate>2018-10-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Brent Faduski as authorized officer of SVLSF V, LLC, the GP of SV Life Sciences Fund V (GP), L.P, the GP of SV Life Sciences Fund V Strategic Partners, L.P.</signatureName>
        <signatureDate>2018-10-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
