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v3.23.1

Organization and Principal Activities - Additional Information (Details) $ in Thousands | 3 Months Ended |
--- | --- | ---
Mar. 31, 2023 USD ($) Segment shares | Mar. 31, 2022 USD ($) | Dec. 31, 2022 USD ($)
Organization Consolidation And Presentation Of Financial Statements [Line Items] |  |  |
Date of incorporation | Apr. 21, 2003 |  |
Headquartered in | South San Francisco |  |
Headquartered in state | CA |  |
Number of operating segments | Segment | 1 |  |
Accumulated deficit | $ 502,665 |  | $ 452,615
Unrestricted cash, cash equivalents and marketable securities | $ 251,500 |  |
Substantial doubt about going concern, within one year | false |  |
Underwriting discounts and commissions and other offering expenses |  | $ 22 |
Vaxcyte |  |  |
Organization Consolidation And Presentation Of Financial Statements [Line Items] |  |  |
Unrestricted cash, cash equivalents and equity securities at carrying value | $ 25,000 |  |
At-the-Market (“ATM") | Common Stock |  |  |
Organization Consolidation And Presentation Of Financial Statements [Line Items] |  |  |
Shares of common stock | shares | 1,641,374 |  |
Gross proceeds from issuance of common stock | $ 11,200 |  |
Underwriting discounts and commissions and other offering expenses | 300 |  |
Net proceeds from issuance of common stock | $ 10,900 |  |
Minimum |  |  |
Organization Consolidation And Presentation Of Financial Statements [Line Items] |  |  |
Period from issuance date of unaudited interim condensed financial statements | 12 months |  |

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