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v3.23.3

Condensed Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2023 | Sep. 30, 2022
Operating activities |  |
Net loss | $ (137,858) | $ (84,610)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 5,085 | 4,162
(Accretion of discount) amortization of premium on marketable securities | (6,022) | 810
Stock-based compensation | 18,685 | 20,452
Non-cash lease expenses | 2,447 | 1,968
Realized gain on sale of equity securities |  | (30)
Unrealized gain on equity securities | (2,023) | (323)
Non-cash interest expense on deferred royalty obligation | 6,378 |
Other | 414 | 144
Changes in operating assets and liabilities: |  |
Accounts receivable | (9,505) | 1,213
Prepaid expenses and other assets | 778 | (2,941)
Accounts payable | 755 | (288)
Accrued compensation | (1,773) | (1,037)
Accrued expenses and other liabilities | 4,579 | 1,329
Deferred revenue | (4,507) | 85,156
Change in operating lease liability | (3,121) | 1,408
Net cash (used in) provided by operating activities | (125,688) | 27,413
Investing activities |  |
Purchases of marketable securities | (379,728) | (114,498)
Maturities of marketable securities | 390,960 | 88,460
Sales of marketable securities | 11,231 | 32,764
Proceed from sale of equity securities |  | 625
Purchases of equipment and leasehold improvements | (2,874) | (4,491)
Net cash provided by investing activities | 19,589 | 2,860
Financing activities |  |
Proceeds from sales of common stock, net of issuance costs | 11,971 | 40,925
Payment of debt | (9,375) | (6,250)
Proceeds from the sale of future royalties, net of issuance costs | 136,208 |
Proceeds from exercise of common stock options | 314 | 267
Taxes paid related to net shares settlement of restricted stock units | (490) | (463)
Proceeds from employee stock purchase plan | 2,051 | 1,613
Net cash provided by financing activities | 140,679 | 36,092
Net increase in cash, cash equivalents and restricted cash | 34,580 | 66,365
Cash, cash equivalents and restricted cash at beginning of period | 48,126 | 31,286
Cash, cash equivalents and restricted cash at end of period | 82,706 | 97,651
Supplemental disclosure of cash flow information: |  |
Cash paid for interest | 971 | 1,442
Supplemental disclosure of non-cash investing and financing information: |  |
Purchases of equipment included in accounts payable and accrued expense | 327 | 1,775
Financing component associated with program fees | $ 7,531 | $ 2,251

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