    <SEC-DOCUMENT>0001144204-18-004431-index.html : 20180301
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    <ACCEPTANCE-DATETIME>20180130090949

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    ACCESSION NUMBER:		0001144204-18-004431

    CONFORMED SUBMISSION TYPE:	F-1/A

    PUBLIC DOCUMENT COUNT:		23

    FILED AS OF DATE:		20180130

    DATE AS OF CHANGE:		20180131

    FILER:

    	COMPANY DATA:

    		COMPANY CONFORMED NAME:			Sol-Gel Technologies Ltd.

    		CENTRAL INDEX KEY:			0001684693

    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]

    		IRS NUMBER:				000000000

    		STATE OF INCORPORATION:			L3

    		FISCAL YEAR END:			1231

    	FILING VALUES:

    		FORM TYPE:		F-1/A

    		SEC ACT:		1933 Act

    		SEC FILE NUMBER:	333-220234

    		FILM NUMBER:		18557583

    	BUSINESS ADDRESS:

    		STREET 1:		7 GOLDA MEIR ST.

    		STREET 2:		WEIZMANN SCIENCE PARK

    		CITY:			NESS ZIONA

    		STATE:			L3

    		ZIP:			7403648

    		BUSINESS PHONE:		97289313433

    	MAIL ADDRESS:

    		STREET 1:		7 GOLDA MEIR ST.

    		STREET 2:		WEIZMANN SCIENCE PARK

    		CITY:			NESS ZIONA

    		STATE:			L3

    		ZIP:			7403648

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    <DESCRIPTION>AMENDMENT NO. 5 TO FORM F-1
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    Document 1 - file: tv483839-f1a.htm

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    Document 2 - file: tv483839_ex5-1.htm

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    <DESCRIPTION>EXHIBIT 10.16
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    Document 3 - file: tv483839_ex10-16.htm

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    Document 4 - file: tv483839_ex23-1.htm

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    <FILENAME>filename24.htm
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