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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
CASH FLOWS FROM OPERATING ACTIVITIES:      
Loss $ (29,290) $ (24,609) $ (32,203)
Adjustments required to reconcile loss to net cash used in operating activities:      
Depreciation 946 887 762
Changes in accrued liability for employee rights upon retirement 21 38 106
Share-based compensation expenses 1,217 2,552 4,654
Net changes in operating leases 71 5
Changes in fair value of marketable securities 138 65 29
Finance expenses, net 12 50 (34)
Changes in operating asset and liabilities:      
Receivables from collaborative arrangements 1,967 (4,120)
Prepaid expenses and other current assets 219 1,694 (1,463)
Accounts payable, accrued expenses and other (542) 938 3,029
Long term receivables 1,653
Net cash used in operating activities (25,241) (22,500) (23,467)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchase of property and equipment (449) (597) (1,052)
Bank deposits (21,400) 1,000 3,000
Restricted long-term deposits (21) (10) 8
Investments in marketable securities (32,322) (38,702) (71,783)
Proceeds from sales and maturity of marketable securities 51,498 54,333 15,092
Net cash provided by (used in) investing activities (2,694) 16,024 (54,735)
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from exercise of options granted to employees 151 44
Proceeds from issuance of shares and warrants through public offering, net of issuance costs 21,306 10,613 78,775
Net proceeds from issuance of shares and warrants to the controlling shareholder through private placement 5,000    
Net cash provided by financing activities 26,457 10,613 78,819
EFFECT OF EXCHANGE RATE ON CASH AND CASH EQUIVALENTS (12) (50) 34
INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS (1,490) 4,087 651
CASH AND CASH EQUIVALENTS AND RESRICTED CASH AT BEGINNING OF THE YEAR 9,762 5,675 5,024
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH AT END OF THE YEAR 8,272 9,762 5,675
Cash and Cash equivalents 7,122 9,412 5,325
Restricted cash 1,150 350 350
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH SHOWN IN STATEMENT OF CASH FLOWS 8,272 9,762 5,675
SUPPLEMENTARY INFORMATION ON INVESTING AND FINANCING ACTIVITIES NOT INVOLVING CASH FLOWS:      
Recognition of new operating lease ROU and liabilities 378 1,329
Conversion of loans from the controlling shareholder 65,338
SUPPLEMENTARY INFORMATION:      
Income taxes paid 7
Interest received $ 770 $ 1,600 $ 1,477