<SEC-DOCUMENT>0001641172-25-025980-index.html : 20250829
<SEC-HEADER>0001641172-25-025980.hdr.sgml : 20250829
<ACCEPTANCE-DATETIME>20250829160524
ACCESSION NUMBER:		0001641172-25-025980
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20250829
DATE AS OF CHANGE:		20250829

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Sol-Gel Technologies Ltd.
		CENTRAL INDEX KEY:			0001684693
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			L3
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-90328
		FILM NUMBER:		251280813

	BUSINESS ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		7 GOLDA MEIR ST.
		STREET 2:		WEIZMANN SCIENCE PARK
		CITY:			NESS ZIONA
		NON US STATE TERRITORY:  	L3
		PROVINCE COUNTRY:   	L3
		ZIP:			7403648
		BUSINESS PHONE:		97289313433

	MAIL ADDRESS:	
		ADDRESS IS A NON US LOCATION: 	YES
		STREET 1:		7 GOLDA MEIR ST.
		STREET 2:		WEIZMANN SCIENCE PARK
		CITY:			NESS ZIONA
		NON US STATE TERRITORY:  	L3
		PROVINCE COUNTRY:   	L3
		ZIP:			7403648

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Opaleye Management Inc.
		CENTRAL INDEX KEY:			0001595855
		ORGANIZATION NAME:           	
		EIN:				205648796
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G

	BUSINESS ADDRESS:	
		STREET 1:		ONE BOSTON PLACE
		STREET 2:		SUITE 2600
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
		BUSINESS PHONE:		617-904-9195

	MAIL ADDRESS:	
		STREET 1:		ONE BOSTON PLACE
		STREET 2:		SUITE 2600
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02108
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
Document 1 - file: primary_doc.html

Document 1 - RAW XML: primary_doc.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>ex99-1.htm
<DESCRIPTION>EX-99.1
<TEXT>
Document 2 - file: ex99-1.htm

</DOCUMENT>
</SEC-DOCUMENT>