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Organization, Business, Basis of Presentation and Summary of Significant Accounting Policies - Additional Information (Detail) - USD ($)
$ in Thousands
 3 Months Ended 12 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Dec. 31, 2023
Description Of Business [Line Items]      
Net loss $ (15,491) $ (11,951)  
Accumulated deficit (483,514)   $ (468,023)
Cash, cash equivalents, restricted cash and available-for-sale investments 87,700    
Restricted cash $ 3,214 $ 3,190 3,484
Employee retention of payroll expenses     1,200
Research and Development Expense [Member]      
Description Of Business [Line Items]      
Employee retention credit receivable - research and development expenses     800
General and Administrative Expense [Member]      
Description Of Business [Line Items]      
Employee retention credit receivable - general and administrative expenses     $ 400
Pangu BioPharma [Member] | Hong Kong [Member]      
Description Of Business [Line Items]      
Majority-owned subsidiary percentage 98.00%