    <SEC-DOCUMENT>0001339970-26-000023-index.html : 20260326
    <SEC-HEADER>0001339970-26-000023.hdr.sgml : 20260326
    <ACCEPTANCE-DATETIME>20260326161033
    ACCESSION NUMBER:		0001339970-26-000023
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20251231
    FILED AS OF DATE:		20260326
    DATE AS OF CHANGE:		20260326
    EFFECTIVENESS DATE:		20260326

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			aTYR PHARMA INC
    		CENTRAL INDEX KEY:			0001339970
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				203435077
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37378
    		FILM NUMBER:		26798315

    	BUSINESS ADDRESS:
    		STREET 1:		10240 SORRENTO VALLEY ROAD
    		STREET 2:		SUITE 300
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    		BUSINESS PHONE:		8587318389

    	MAIL ADDRESS:
    		STREET 1:		10240 SORRENTO VALLEY ROAD
    		STREET 2:		SUITE 300
    		CITY:			SAN DIEGO
    		STATE:			CA
    		ZIP:			92121
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>2025annual_report.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: 2025annual_report.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>