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Organization, Business, Basis of Presentation and Summary of Significant Accounting Policies (Tables) | 3 Months Ended
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Mar. 31, 2026
Accounting Policies [Abstract] |
Schedule of Potentially Dilutive Securities Not Considered for Calculation of Diluted Net Loss Per Share | Potentially dilutive securities not considered for the calculation of diluted net loss per share are as follows (in common stock equivalents):
|  | March 31, |
|  | 2026 |  |  | 2025 |
Common stock options and restricted stock units |  |  | 13,835,392 |  |  |  | 9,420,566 |
Employee stock purchase plan |  |  | 40,707 |  |  |  | 34,143 |
Total |  |  | 13,876,099 |  |  |  | 9,454,709 |
Summary of Significant Expense Categories Reviewed by CODM | The table below summarizes the significant expense categories regularly reviewed by our CODM for the three months ended March 31, 2026 and 2025.
|  | Three Months Ended March 31, |
|  | 2026 |  |  | 2025 |
Research and development expenses: |  |  |  |  |  |
Efzofitimod expenses |  | $ | 3,535 |  |  | $ | 8,804 |
Preclinical development and other shared research and development expenses |  |  | 3,355 |  |  |  | 2,560 |
Non-cash expenses (depreciation and stock-based compensation) |  |  | 427 |  |  |  | 450 |
Total research and development expenses |  |  | 7,317 |  |  |  | 11,814 |
General and administrative expenses: |  |  |  |  |  |
Other general and administrative expenses |  |  | 3,076 |  |  |  | 3,064 |
Non-cash expenses (depreciation and stock-based compensation) |  |  | 1,043 |  |  |  | 895 |
Total general and administrative expenses |  |  | 4,119 |  |  |  | 3,959 |
Other segment items (1) |  |  | 644 |  |  |  | 892 |
Consolidated net loss |  | $ | (10,792 | ) |  | $ | (14,881 | )
(1) Other segment items includes interest income and interest expense. |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482662/260-10-50-1 + Details
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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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