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STATEMENTS OF CASH FLOWS (UNAUDITED) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Cash flows used in operating activities:    
Net loss $ (32,085) $ (31,431)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 435 426
Noncash lease expense 384 414
Stock-based compensation 3,832 5,547
Amortization of premium and discount on marketable securities, net 79 (1,541)
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (1,048) (788)
Accounts payable (1,910) 631
Accrued expenses and other liabilities (3,968) (5,692)
Operating lease liabilities 50 643
Net cash used in operating activities (34,231) (31,791)
Cash flows provided by investing activities:    
Purchases of marketable securities (9,463) (5,490)
Proceeds from maturities of marketable securities 71,696 37,000
Purchases of property and equipment (47) (289)
Net cash provided by investing activities 62,186 31,221
Cash flows used in financing activities:    
Proceeds from the issuance of common stock in connection with the exercise of stock options   2
Payment of withholding taxes related to stock-based compensation to employees (5) (16)
Principal payments on finance lease liabilities (155)  
Net cash used in financing activities (160) (14)
Net increase (decrease) in cash, cash equivalents and restricted cash 27,795 (584)
Cash, cash equivalents, and restricted cash at beginning of period 16,518 29,335
Cash, cash equivalents, and restricted cash at end of period 44,313 28,751
Supplemental disclosures of non-cash activities:    
Property and equipment in accounts payable and accrued expenses and other current liabilities 19 269
Unrealized loss on marketable securities $ (23) $ (458)