<SEC-DOCUMENT>0001825005-26-000002-index.html : 20260205
<SEC-HEADER>0001825005-26-000002.hdr.sgml : 20260205
<ACCEPTANCE-DATETIME>20260205161415
ACCESSION NUMBER:		0001825005-26-000002
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20260204
FILED AS OF DATE:		20260205
DATE AS OF CHANGE:		20260205

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Combs Andrew
		CENTRAL INDEX KEY:			0001825005
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39527
		FILM NUMBER:		26603052

	MAIL ADDRESS:	
		STREET 1:		C/O PRELUDE THERAPEUTICS INCORPORATED
		STREET 2:		200 POWDER MILL ROAD
		CITY:			WILMINGTON
		STATE:			DE
		ZIP:			19803

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Prelude Therapeutics Inc
		CENTRAL INDEX KEY:			0001678660
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				811384762
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		175 INNOVATION BOULEVARD
		CITY:			WILMINGTON
		STATE:			DE
		ZIP:			19805
		BUSINESS PHONE:		(302) 467-1280

	MAIL ADDRESS:	
		STREET 1:		175 INNOVATION BOULEVARD
		CITY:			WILMINGTON
		STATE:			DE
		ZIP:			19805

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Prelude Therapeutics Inc.
		DATE OF NAME CHANGE:	20160630
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>primarydocument.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
Document 1 - file: primarydocument.html

Document 1 - RAW XML: primarydocument.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>acombspoa.txt
<DESCRIPTION>POA
<TEXT>
Document 2 - file: acombspoa.txt

</DOCUMENT>
</SEC-DOCUMENT>