    <SEC-DOCUMENT>0001104659-20-076103-index.html : 20200623
    <SEC-HEADER>0001104659-20-076103.hdr.sgml : 20200623
    <ACCEPTANCE-DATETIME>20200623165551
    ACCESSION NUMBER:		0001104659-20-076103
    CONFORMED SUBMISSION TYPE:	486BPOS
    PUBLIC DOCUMENT COUNT:		13
    FILED AS OF DATE:		20200623
    DATE AS OF CHANGE:		20200623
    EFFECTIVENESS DATE:		20200623

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Destra Multi-Alternative Fund
    		CENTRAL INDEX KEY:			0001523289
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE

    	FILING VALUES:
    		FORM TYPE:		486BPOS
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-189008
    		FILM NUMBER:		20982809

    	BUSINESS ADDRESS:
    		STREET 1:		80 ARKAY DRIVE
    		CITY:			HAUPPAUGE
    		STATE:			NY
    		ZIP:			11788
    		BUSINESS PHONE:		631-470-2600

    	MAIL ADDRESS:
    		STREET 1:		80 ARKAY DRIVE
    		CITY:			HAUPPAUGE
    		STATE:			NY
    		ZIP:			11788

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Multi-Strategy Growth & Income Fund
    		DATE OF NAME CHANGE:	20110614

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Destra Multi-Alternative Fund
    		CENTRAL INDEX KEY:			0001523289
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE

    	FILING VALUES:
    		FORM TYPE:		486BPOS
    		SEC ACT:		1940 Act
    		SEC FILE NUMBER:	811-22572
    		FILM NUMBER:		20982808

    	BUSINESS ADDRESS:
    		STREET 1:		80 ARKAY DRIVE
    		CITY:			HAUPPAUGE
    		STATE:			NY
    		ZIP:			11788
    		BUSINESS PHONE:		631-470-2600

    	MAIL ADDRESS:
    		STREET 1:		80 ARKAY DRIVE
    		CITY:			HAUPPAUGE
    		STATE:			NY
    		ZIP:			11788

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Multi-Strategy Growth & Income Fund
    		DATE OF NAME CHANGE:	20110614
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>486BPOS
    <SEQUENCE>1
    <FILENAME>tm2021250d2_486bpos.htm
    <DESCRIPTION>486BPOS
    <TEXT>
    Document 1 - file: tm2021250d2_486bpos.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.(K)(1)
    <SEQUENCE>2
    <FILENAME>tm2021250d2_ex-k1.htm
    <DESCRIPTION>ADMINISTRATION AND FUND ACCOUNTING AGREEMENT
    <TEXT>
    Document 2 - file: tm2021250d2_ex-k1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.(K)(2)
    <SEQUENCE>3
    <FILENAME>tm2021250d2_ex-k2.htm
    <DESCRIPTION>FORM OF AMENDED AND RESTATED EXPENSE LIMITATION AGREEMENT
    <TEXT>
    Document 3 - file: tm2021250d2_ex-k2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.(L)(2)
    <SEQUENCE>4
    <FILENAME>tm2021250d2_ex-l2.htm
    <DESCRIPTION>CONSENT OF FAEGRE DRINKER BIDDLE & REATH LLP
    <TEXT>
    Document 4 - file: tm2021250d2_ex-l2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.(N)
    <SEQUENCE>5
    <FILENAME>tm2021250d2_ex-n.htm
    <DESCRIPTION>CONSENT OF COHEN & COMPANY, LTD.
    <TEXT>
    Document 5 - file: tm2021250d2_ex-n.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.(R)(2)
    <SEQUENCE>6
    <FILENAME>tm2021250d2_ex-r2.htm
    <DESCRIPTION>CODE OF ETHICS
    <TEXT>
    Document 6 - file: tm2021250d2_ex-r2.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>lg_destra-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 8 - file: lg_destra-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>sg_cohen-bw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 9 - file: sg_cohen-bw.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>tm2021250d1-lc_destrabw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 10 - file: tm2021250d1-lc_destrabw.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>tm2021250d2_ex-r2img001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 11 - file: tm2021250d2_ex-r2img001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>tm2021250d2_ex-r2img002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 12 - file: tm2021250d2_ex-r2img002.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>tm2021250d2_ex-r2img003.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 13 - file: tm2021250d2_ex-r2img003.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>tm2021250d2_ex-r2img004.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 14 - file: tm2021250d2_ex-r2img004.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>