    <SEC-DOCUMENT>0001104659-20-076863-index.html : 20200625
    <SEC-HEADER>0001104659-20-076863.hdr.sgml : 20200625
    <ACCEPTANCE-DATETIME>20200625161809
    ACCESSION NUMBER:		0001104659-20-076863
    CONFORMED SUBMISSION TYPE:	497
    PUBLIC DOCUMENT COUNT:		4
    FILED AS OF DATE:		20200625
    DATE AS OF CHANGE:		20200625
    EFFECTIVENESS DATE:		20200625

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Destra Multi-Alternative Fund
    		CENTRAL INDEX KEY:			0001523289
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE

    	FILING VALUES:
    		FORM TYPE:		497
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-189008
    		FILM NUMBER:		20989461

    	BUSINESS ADDRESS:
    		STREET 1:		80 ARKAY DRIVE
    		CITY:			HAUPPAUGE
    		STATE:			NY
    		ZIP:			11788
    		BUSINESS PHONE:		631-470-2600

    	MAIL ADDRESS:
    		STREET 1:		80 ARKAY DRIVE
    		CITY:			HAUPPAUGE
    		STATE:			NY
    		ZIP:			11788

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Multi-Strategy Growth & Income Fund
    		DATE OF NAME CHANGE:	20110614
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>497
    <SEQUENCE>1
    <FILENAME>tm2021250-3_497.htm
    <DESCRIPTION>497
    <TEXT>
    Document 1 - file: tm2021250-3_497.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>lg_destra-4c.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: lg_destra-4c.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>tm2021250d1-lc_destrabw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: tm2021250d1-lc_destrabw.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>sg_cohen-bw.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 5 - file: sg_cohen-bw.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>