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Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Operating Expenses:      
Research and development $ 36,493 $ 23,933 $ 20,759
General and administrative 21,800 11,009 5,878
Total operating expenses 58,293 34,942 26,637
Loss from operations (58,293) (34,942) (26,637)
Other income (expense):      
Interest income, net 449 651 1,301
Other income (expense) 21 (143) (8)
Total other income (expense) 470 508 1,293
Loss before provision for income taxes (57,823) (34,434) (25,344)
Provision for income taxes 23 6 8
Net loss (57,846) (34,440) (25,352)
Unrealized (losses) gains on marketable securities, net of tax (78) 3 10
Comprehensive loss $ (57,924) $ (34,437) $ (25,342)
Net loss per share—basic and diluted $ (1.28) $ (2.40) $ (8.35)
Weighted-average common shares outstanding 45,137,656 14,364,475 3,035,243