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Condensed Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash flows from operating activities:    
Net loss $ (36,564) $ (35,743)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 6,085 4,695
Depreciation 540 166
(Accretion) amortization of premiums on marketable securities (1,669) 126
Non-cash lease (income) expense (188) 180
Other, net   (88)
Change in operating assets and liabilities:    
Prepaid expenses and other assets 2,758 (308)
Operating lease right-of-use assets and liabilities   1,612
Accounts payable 493 (1,342)
Accrued expenses 632 (975)
Net cash used in operating activities (27,913) (31,677)
Cash flows from investing activities:    
Purchases of property and equipment (721) (4,296)
Purchases of marketable securities (129,552) (149,223)
Maturities of marketable securities 115,955 99,415
Net cash used in investing activities (14,318) (54,104)
Cash flows from financing activities:    
Issuance of common stock, net of issuance costs 2,026  
Proceeds from the exercise of stock options and common stock issued under the 2020 ESPP 117 404
Net cash provided by financing activities 2,143 404
Net decrease in cash and cash equivalents (40,088) (85,377)
Cash, cash equivalents, and restricted cash    
Cash, cash equivalents, and restricted cash - beginning of period 109,119 173,289
Cash, cash equivalents, and restricted cash - end of period $ 69,031 87,912
Supplemental disclosures of noncash investing activities    
Accrued purchases of property and equipment   $ 1,501