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Nature of the Business and Basis of Presentation - Additional Information (Detail)
$ in Millions
3 Months Ended
May 14, 2019
USD ($)
Mar. 31, 2019
Mar. 13, 2019
Schedule Of Accounting Policies [Line Items]      
Percentage of common stock owned     63.70%
Net proceeds from sale of common stock and pre-funded warrants $ 79    
Arsanis [Member]      
Schedule Of Accounting Policies [Line Items]      
Business acquisition share exchange ratio   0.5702