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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2024 | Mar. 31, 2023
Cash flows from operating activities: |  |
Net loss | $ (51,766) | $ (24,020)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation expense | 1,739 | 1,645
Depreciation and amortization expense | 62 | 127
Non-cash lease expense | 386 | 385
Accretion of debt discount | 254 | 225
Change in fair value of warrant liability | 13,755 | (5,439)
Other | (117) | (51)
Changes in operating assets and liabilities: |  |
Prepaid expenses, other current assets and research and development incentive receivable | 1,062 | 2,084
Accounts payable | 4 | (1,714)
Accrued expenses and other long-term liabilities | 1,264 | 496
Lease liabilities | (240) | (250)
Net cash used in operating activities | (33,597) | (26,512)
Cash flows from investing activities: |  |
Payments to Acquire Marketable Securities | (10,263) | 0
Sales and maturities of marketable securities | 5,000 | 0
Acquisition of property and equipment | (59) | (9)
Net cash used in investing activities | (5,322) | (9)
Cash flows from financing activities: |  |
Fees paid to amendment loan and security agreement and issuance costs related to the sale of warrants | 0 | (381)
Repayments of Secured Debt | 0 | (1,300)
Proceeds from sale of common stock, warrants and pre-funded warrants, net of issuance costs | 0 | (443)
Net cash used in financing activities | 0 | (2,124)
Effect of exchange rate changes on cash, cash equivalents and restricted cash | (59) | 50
Net decrease in cash, cash equivalents and restricted cash | (38,978) | (28,595)
Cash, cash equivalents and restricted cash at beginning of period | 100,248 | 123,028
Cash, cash equivalents and restricted cash at end of period | $ 61,270 | $ 94,433

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- Definition The cash outflow to repay long-term debt that is wholly or partially secured by collateral. Excludes repayments of tax exempt secured debt. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 15 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482740/230-10-45-15 + Details
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- Definition Amount of noncash expense for share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 28 -Subparagraph (a) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28 + Details
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- Definition Increase decrease in lease liabilities. + References No definition available. + Details
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- Definition Issuance costs Related To Sale Of Warrants And Fees Paid For Amendments To Loan And Security Agreement + References No definition available. + Details
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- Definition Non-cash interest expense. + References No definition available. + Details
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- Definition Non-cash lease expense. + References No definition available. + Details
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- Definition Proceeds from Issuance or Sale of Equity, Net of Issuance Costs + References No definition available. + Details
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