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14. Shareholders' Equity (Tables)
 3 Months Ended 12 Months Ended
Mar. 31, 2014
Dec. 31, 2013
Shareholders' equity    
Common stock outstanding
    Number of  
    Common Shares  
Balance at December 31, 2012     890,837  
         
Conversion of Series E Preferred to common stock     1,575,000  
Shares issued for acquisition of Canterbury and Hygeia     1,150,116  
Conversion of warrants to common stock     1,023,264  
Conversion of debt to common stock     576,331  
Issuance of shares for advisory agreements     243,250  
Issuance of shares to third party for assumption of liabilities     200,000  
Issuance of common stock for cash     142,501  
Other     12,486  
Balance at December 31, 2013     5,813,785  
         
Issuance of shares to third party for assumption of liabilities     150,000  
Shares issued for acquisition of Paloma     2,500,000  
Shares issued for acquisition of VasculoMedics     220,000  
Balance at March 31, 2014 (unaudited)     8,683,785  

   
    Number of Common Shares  
Balance at December 31, 2012     890,837  
         
Conversion of Series E Preferred to common stock     1,575,000  
Shares issued for acquisition     1,150,116  
Conversion of warrants to common stock     1,023,264  
Conversion of debt to common stock     576,331  
Issuance of shares for advisory agreements     243,250  
Issuance of shares to third party for assumption of liabilities     200,000  
Issuance of common stock for cash     142,501  
Other     12,486  
Balance at December 31, 2013     5,813,785  
Stock Options- Assumptions

The assumptions used to value the options granted during the first three months of 2014 was:

 

Estimated fair value of underlying common stock     $2.50 - $3.00  
Remaining life     5.0  
Risk-free interest rate     1.50% - 1.72%  
Expected volatility     153% - 155%  
Dividend yield     –  

 

The Black Scholes expense for these March 27, 2013 options was calculated using the following assumptions. The fair value of the underlying common stock was based on the sale of 139,167 shares of common stock at $3.00 by the Company during the three months ended June 30, 2013.

 

Estimated fair value of underlying common stock     $3.00  
Remaining life     5.0  
Risk-free interest rate     0.35%  
Expected volatility     141%  
Dividend yield     –  

 

The Black Scholes expense for these 2012 options was calculated using the following assumptions. The fair value of the underlying common stock was determined by closing price on the Bulletin Board stock exchange.

 

Estimated fair value of underlying common stock     $35.00 - $38.00  
Remaining life     5.0  
Risk-free interest rate     0.69% - 0.80%  
Expected volatility     80% - 89%  
Dividend yield     –  
Stock Options - Activity

The following table sets forth the activity of our stock options to purchase common stock:

 

    Options Outstanding     Options Exercisable  
                Weighted                 Weighted        
                Average     Weighted           Average     Weighted  
          Range of     Remaining     Average           Remaining     Average  
    Options     Exercise     Life in     Exercise     Options     Life in     Exercise  
    Outstanding     Prices     Years     Price     Exercisable     Years     Price  
As of December 31, 2012     79,436       $35.00 -$54.00        3.0     $ 46.00       57,310       2.6     $ 48.00  
Canceled     –       –       –       –       –       –       –  
Exercised     –       –       –       –       –       –       –  
Granted     310,000       $3.00       4.2     $ 3.00       310,000       4.2     $ 3.00  
As of December 31, 2013     389,436        $3.00 -$54.00        3.9     $ 11.77       367,310       3.9     $ 11.10  
Canceled     3,585       –       –       43.27       3,585       –       43.27  
Exercised     –       –       –       –       –       –       –  
Granted     600,586       $2.50 - $3.00       4.9     $ 3.00       91,128       4.9     $ 3.00  
As of March 31, 2014     986,437        $3.00 -$54.00        4.4     $ 6.74       454,853       3.8     $ 11.11  

 
      Options Outstanding     Options Exercisable  
                      Weighted                     Weighted          
                      Average     Weighted             Average     Weighted  
              Range of     Remaining     Average             Remaining     Average  
      Options     Exercise     Life in     Exercise     Options     Life in     Exercise  
      Outstanding     Prices     Years     Price     Exercisable     Years     Price  
As of December 31, 2011       121,699     $14.00 - $150.00       2.9       $49.00       87,577       2.9     $ 40.00  
Cancelled       (72,763 )     –       –       –       (46,610 )     –       –  
Exercised       –       –       –       –       –       –       –  
Granted       30,500     $35.00 - $38.00       4.2       $36.00       16,343       4.2     $ 36.00  
As of December 31, 2012       79,436     $35.00 - $54.00       3.0       $46.00       57,310       2.6     $ 48.00  
Cancelled       –       –       –       –       –       –       –  
Exercised       –       –       –       –       –       –       –  
Granted       310,000       $3.00       4.2       $3.00       310,000       4.2       $3.00  
As of December 31, 2013       389,436       $0.03 - $0.54       3.9       $11.77       367,310       3.9       $11.10  
Warrants -Assumptions

  

Estimated fair value of underlying common stock     $3.00  
Remaining life     5.0  
Risk-free interest rate     0.35%  
Expected volatility     141%  
Dividend yield     –  

 

The Black Scholes expense for these March 27, 2013 warrants was calculated using the following assumptions. The fair value of the underlying common stock was based on the sale of 139,167 shares of common stock at $3.00 by the Company during the three months ended June 30, 2013.

  

Estimated fair value of underlying common stock     $3.00  
Remaining life     5.0  
Risk-free interest rate     0.35%  
Expected volatility     141%  
Dividend yield     –  

 

The Black Scholes expense for these 2012 warrants was calculated using the following assumptions. The fair value of the underlying common stock was determined by closing price on the Bulletin Board stock exchange. 

 

Estimated fair value of underlying common stock     $38.00 - $75.00  
Remaining life     5.0  
Risk-free interest rate     0.74% - 1.80%  
Expected volatility     84% - 132%  
Dividend yield     –  
Warrants - Summary

A summary of the warrants:

 

    Warrants Outstanding     Warrants Exercisable  
                Weighted                 Weighted        
                Average     Weighted           Average     Weighted  
          Range of     Remaining     Average           Remaining     Average  
    Warrants     Exercise     Life in     Exercise     Warrants     Life in     Exercise  
    Outstanding     Prices     Years     Price     Exercisable     Years     Price  
As of December 31, 2012     1,322,852       $30.00 - $200.00       3.2     $ 40.00       1,269,102       3.2     $ 38.00  
Canceled     (978,700 )     $30.00       –     $ 30.00       (939,950 )     –     $ 30.00  
Exercised     –       –       –       –       –       –       –  
Granted     173,917       $3.00       4.2     $ 3.00       173,917       4.2     $ 3.00  
As of December 31, 2013     518,069       $3.00 - $200.00       3.3     $ 44.07       503,069       3.3     $ 44.07  
Canceled     198       –       –     $ 200.00       198       –     $ 200.00  
Exercised     –       –       –       –       –       –       –  
Granted     –       –       –       –       –       –       –  
As of March 31, 2014     517,871       $3.00 - $200.00       3.0     $ 44.01       502,871       3.0     $ 44.01  

 
      Warrants Outstanding     Warrants Exercisable  
                      Weighted                     Weighted          
                      Average     Weighted               Average     Weighted  
              Range of     Remaining     Average             Remaining     Average  
      Warrants     Exercise     Life in     Exercise     Warrants     Life in     Exercise  
      Outstanding     Prices     Years     Price     Exercisable     Years     Price  
As of December 31, 2011       595,302     $65.00 - $200.00       3.2       $200.00       595,302       3.2       $200.00  
Exercised       –       –       –       –       –       –       –  
Ratchet-down impact       569,917       $30.00       –       $30.00       569,917       –       $30.00  
Granted       157,633     $30.00 - $75.00       4.3       $38.00       103,883       4.3       –  
As of December 31, 2012       1,322,852     $30.00 - $200.00       3.2       $40.00       1,269,102       3.2       $38.00  
Exercised       (978,700 )     $30.00       –       $30.00       (939,950 )     –       $30.00  
Ratchet-down impact       –       –       –       –       –       –       –  
Granted       173,917       $3.00       4.2       $3.00       173,917       4.2       $3.00  
As of December 31, 2013       518,069     $3.00 - $200.00       3.3       $44.07       503,069       3.3       $44.07