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Note 15 - Investment in Or-Genix Therapeutics, Inc. (Details Textual) - USD ($) |  | 12 Months Ended
--- | --- | ---
Apr. 30, 2015 | Dec. 31, 2015 | Dec. 31, 2014
Or Genix Therapeutics Inc [Member] |  |  |
Cost Method Ownership Percentage | 19.90% |  |
Investment in Common Stock Shares | 2,484,395 |  |
Payments to Acquire Investments | $ 250,000 |  |
Payments to Acquire Investments |  | $ 250,000 |

X
- Definition The percentage of ownership of common stock or equity participation in the investee accounted for under the cost method. + References No definition available. + Details
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Namespace Prefix: | dffn_
Data Type: | num:percentItemType
Balance Type: | na
Period Type: | instant

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- Definition Represents the shares of common stock acquired. + References No definition available. + Details
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Data Type: | xbrli:sharesItemType
Balance Type: | na
Period Type: | duration

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- Definition The cash outflow associated with the purchase of all investments (debt, security, other) during the period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Investing Activities -URI http://asc.fasb.org/extlink&oid=6516133 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 13 -URI http://asc.fasb.org/extlink&oid=56944662&loc=d3e3213-108585 + Details
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Balance Type: | credit
Period Type: | duration

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- Details
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Namespace Prefix: |
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