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Note 11 - Commitments and Contingencies - Contractual Obligations (Details)	Dec. 31, 2015 USD ($)
Payments due by period:
One year	$ 72,920
Two years	74,355
Three years	12,432
Total	$ 159,707

X

- Definition

Amount of contractual obligation maturing in the next rolling twelve months following the latest balance sheet. For interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date.

+ References

No definition available.

+ Details

Name:	dffn_ContractualObligationDueInNextRollingTwelveMonths
Namespace Prefix:	dffn_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

X

- Definition

Amount of contractual obligation maturing in the third rolling twelve months following the latest balance sheet. For interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date.

+ References

No definition available.

+ Details

Name:	dffn_ContractualObligationDueInNextRollingYearThree
Namespace Prefix:	dffn_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

X

- Definition

Amount of contractual obligation maturing in the second rolling twelve months following the latest balance sheet. For interim and annual periods when interim periods are reported on a rolling approach, from latest balance sheet date.

+ References

No definition available.

+ Details

Name:	dffn_ContractualObligationDueInNextRollingYearTwo
Namespace Prefix:	dffn_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

X

- References

No definition available.

+ Details

Name:	dffn_ContractualObligationRollingMaturityAbstract
Namespace Prefix:	dffn_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Amount of contractual obligation, including but not limited to, long-term debt, capital lease obligations, operating lease obligations, purchase obligations, and other commitments.

+ References

No definition available.

+ Details

Name:	us-gaap_ContractualObligation
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant