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Note 3 - Basis of Presentation and Summary of Significant Accounting Policies (Tables)
6 Months Ended
Jun. 30, 2016
Notes Tables  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
 
 
June 30,
 
 
 
2016
 
 
2015
 
Convertible debt
    2,115,407       58,534,765  
Common stock warrants
    4,612,089        
Stock options
    17,879,116       11,095,734  
Unvested restricted stock awards
    122,725       184,093  
      24,729,337       69,814,592