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Note 4 - Acquisitions (Tables) | 12 Months Ended
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Dec. 31, 2016
Notes Tables |
Business Combination, Preliminary Purchase Price Consideration [Table Text Block] |
Fair value of the Company’s pre-Merger shares outstanding |  | $ | 19,546,000 |
Estimated fair value of the Company’s pre-Merger stock options outstanding |  |  | 1,321,000 |
Estimated fair value of the Company’s pre-Merger warrants outstanding |  |  | 384,000 |
CVRs – RES-440 product candidate |  |  | 10,000 |
Total purchase price |  | $ | 21,261,000 |
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block] |
Cash and cash equivalents |  | $ | 8,500,602 |
Prepaid expenses and other assets |  |  | 195,200 |
Property and equipment |  |  | 57,531 |
Intangible assets |  |  | 9,600,000 |
Goodwill |  |  | 6,929,258 |
Accrued liabilities |  |  | (377,432 | )
Deferred tax liability |  |  | (3,644,159 | )
Net assets acquired |  | $ | 21,261,000 |
Business Acquisition, Pro Forma Information [Table Text Block] |
|  | Year ended December 3 1 , |
|  | 2016 |  |  | 2015 |
Net revenues |  | $ | — |  |  | $ | — |
Net loss |  | $ | (16,471,398 | ) |  | $ | (17,618,292 | )
Basic and diluted loss per share |  | $ | (1.60 | ) |  | $ | (3.89 | )

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