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Basis of Presentation and Summary of Significant Accounting Policies - Outstanding Dilutive Securities (Details) - shares
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Anti-dilutive securities (in shares) 29,471,085 2,715,984
Convertible debt    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Anti-dilutive securities (in shares) 766,351 428,134
Convertible preferred stock    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Anti-dilutive securities (in shares) 12,376,329 0
Common stock warrants    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Anti-dilutive securities (in shares) 14,016,608 477,688
Stock options    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Anti-dilutive securities (in shares) 2,304,132 1,796,360
Unvested restricted stock awards    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Anti-dilutive securities (in shares) 7,665 13,802