    <SEC-DOCUMENT>0001437749-17-001147-index.html : 20170126
    <SEC-HEADER>0001437749-17-001147.hdr.sgml : 20170126
    <ACCEPTANCE-DATETIME>20170126155116
    ACCESSION NUMBER:		0001437749-17-001147
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		50
    CONFORMED PERIOD OF REPORT:	20170123
    ITEM INFORMATION:		Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year
    ITEM INFORMATION:		Regulation FD Disclosure
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20170126
    DATE AS OF CHANGE:		20170126

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Diffusion Pharmaceuticals Inc.
    		CENTRAL INDEX KEY:			0001053691
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				300645032
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37942
    		FILM NUMBER:		17549654

    	BUSINESS ADDRESS:
    		STREET 1:		2020 AVON COURT
    		STREET 2:		SUITE 4
    		CITY:			CHARLOTTESVILLE
    		STATE:			VA
    		ZIP:			22902
    		BUSINESS PHONE:		(434) 220-0718

    	MAIL ADDRESS:
    		STREET 1:		2020 AVON COURT
    		STREET 2:		SUITE 4
    		CITY:			CHARLOTTESVILLE
    		STATE:			VA
    		ZIP:			22902

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	RestorGenex Corp
    		DATE OF NAME CHANGE:	20140307

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Stratus Media Group, Inc
    		DATE OF NAME CHANGE:	20080722

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	FERIS INTERNATIONAL, INC.
    		DATE OF NAME CHANGE:	20080228
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>dffn20170125_8k.htm
    <DESCRIPTION>FORM 8-K
    <TEXT>
    Document 1 - file: dffn20170125_8k.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-3.1
    <SEQUENCE>2
    <FILENAME>ex3-1.htm
    <DESCRIPTION>EXHIBIT 3.1
    <TEXT>
    Document 2 - file: ex3-1.htm

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    <DESCRIPTION>EXHIBIT 99.1
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    Document 47 - file: a2.jpg

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    Document 49 - file: b2.jpg

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    Document 50 - file: b1.jpg

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