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Note 4 - Acquisition (Tables) | 12 Months Ended
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Dec. 31, 2017
Notes Tables |
Business Combination, Preliminary Purchase Price Consideration [Table Text Block] |
Fair value of the Company ’s pre-Merger shares outstanding |  | $ | 19,546,000 |
Estimated fair value of the Company ’s pre-Merger stock options outstanding |  |  | 1,321,000 |
Estimated fair value of the Company ’s pre-Merger warrants outstanding |  |  | 384,000 |
CVRs – RES-440 product candidate |  |  | 10,000 |
Total purchase price |  | $ | 21,261,000 |
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block] |
Cash and cash equivalents |  | $ | 8,500,602 |
Prepaid expenses and other assets |  |  | 195,200 |
Property and equipment |  |  | 57,531 |
Intangible assets |  |  | 9,600,000 |
Goodwill |  |  | 6,929,258 |
Accrued liabilities |  |  | (377,432 | )
Deferred tax liability |  |  | (3,644,159 | )
Net assets acquired |  | $ | 21,261,000 |
Business Acquisition, Pro Forma Information [Table Text Block] |
|  | Year ended December 31, 2016 |
Net revenues |  | $ | — |
Net loss |  | $ | (16,471,398 | )
Basic and diluted loss per share |  | $ | (1.60 | )

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- Definition Tabular disclosure of the amounts recognized as of the acquisition date for each major class of assets acquired and liabilities assumed. May include but not limited to the following: (a) acquired receivables; (b) contingencies recognized at the acquisition date; and (c) the fair value of noncontrolling interests in the acquiree. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=84161108&loc=d3e4845-128472 + Details
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