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Note 3 - Basis of Presentation and Summary of Significant Accounting Policies - Basic and Diluted Earnings Per Share (Details) - USD ($)
 3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Net (loss) income $ (6,719,730) $ 5,096,856 $ (12,798,872) $ (3,154,181)
Accretion of Series A cumulative preferred dividends (366,641) (85,993) (912,946)
Undistributed earnings to participating securities (1,838,354)
Deemed dividend related to the make-whole provision for the conversion of Series A preferred stock into common (8,167,895)
Net (loss) income attributable to common $ (6,719,730) $ 2,891,861 $ (21,052,760) $ (4,067,127)
Weighted average shares outstanding, basic (in shares) 50,572,001 13,937,869 47,777,757 11,709,128
Net (loss) income per share of common stock, basic (in dollars per share) $ (0.13) $ 0.21 $ (0.44) $ (0.35)
Change in fair value of warrant liability $ (18,909,792)
Interest on convertible debt 28,891
Diluted net loss $ (6,719,730) $ 2,920,752 $ (21,052,760) $ (22,976,919)
Common stock equivalents arising from stock options (in shares) 20,608
Common stock equivalents arising from warrants (in shares) 816,579
Common stock equivalents arising from convertible debt (in shares) 756,376
Common stock equivalents (in shares) 50,572,001 14,714,853 47,777,757 12,525,707
Net (loss) income per share of common stock, diluted (in dollars per share) $ (0.13) $ 0.20 $ (0.44) $ (1.83)