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Note 3 - Basis of Presentation and Summary of Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2018
Notes Tables |
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] |
|  | Year ended December 31, |
|  | 2018 |  |  | 2017 |
Basic net loss per common share calculation: |  |  |  |  |  |  |  |
Net loss |  | $ | (18,369,810 | ) |  | $ | (1,364,518 | )
Accretion of Series A cumulative preferred dividends |  |  | (85,993 | ) |  |  | (1,252,394 | )
Deemed dividend related to the make-whole provision for the conversion of Series A convertible preferred stock into common stock |  |  | (8,167,895 | ) |  |  | — |
Net loss attributable to common stockholders |  | $ | (26,623,698 | ) |  | $ | (2,616,912 | )
Weighted average shares outstanding, basic |  |  | 3,242,301 |  |  |  | 827,575 |
Net loss per share of common, basic |  | $ | (8.21 | ) |  | $ | (3.16 | )
Diluted net loss per common share calculation: |  |  |  |  |  |  |  |
Net loss attributable to common stockholders |  |  | (26,623,698 | ) |  |  | (2,616,912 | )
Change in fair value of warrant liability |  |  | — |  |  |  | (22,072,322 | )
Diluted net loss |  |  | (26,623,698 | ) |  |  | (24,689,234 | )
Weighted average common shares outstanding, basic |  |  | 3,242,301 |  |  |  | 827,575 |
Common stock equivalents arising from warrants |  |  | — |  |  |  | 20,515 |
Common stock equivalents |  |  | 3,242,301 |  |  |  | 848,090 |
Net loss per share of common stock, diluted |  | $ | (8.21 | ) |  | $ | (29.11 | )
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] |
|  | December 31, |
|  | 2018 |  |  | 2017 |
Convertible debt |  |  | — |  |  |  | 14,292 |
Common stock warrants |  |  | 2,087,012 |  |  |  | 29,848 |
Convertible preferred stock |  |  | — |  |  |  | 553,752 |
Stock options |  |  | 203,736 |  |  |  | 170,461 |
Unvested restricted stock awards |  |  | — |  |  |  | 204 |
|  |  | 2,290,748 |  |  |  | 768,557 |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 + Details
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- Definition Tabular disclosure of an entity's basic and diluted earnings per share calculations, including a reconciliation of numerators and denominators of the basic and diluted per-share computations for income from continuing operations. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 + Details
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