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Consolidated Statements of Changes in Stockholders' Equity - USD ($) | Pre-funded Warrants [Member] Preferred Stock [Member] Series A Preferred Stock [Member] | Pre-funded Warrants [Member] Common Stock [Member] | Pre-funded Warrants [Member] | Preferred Stock [Member] Series A Preferred Stock [Member] | Common Stock [Member] | Additional Paid-in Capital [Member] | Retained Earnings [Member] | Total
--- | --- | --- | --- | --- | --- | --- | --- | ---
Balance (in shares) at Dec. 31, 2017 |  |  |  | 8,306,278 | 967,976 |  |  |
Balance at Dec. 31, 2017 |  |  |  |  | $ 968 | $ 82,783,865 | $ (61,554,889) | $ 21,229,944
Conversion of Series A convertible preferred stock to common stock (in shares) |  |  |  | (8,306,278) | 553,752 |  |  |
Conversion of Series A convertible preferred stock to common stock |  |  |  |  | $ 554 | (554) |  |
Issuance of common stock to Series A convertible preferred stockholders under make-whole adjustment feature (in shares) |  |  |  |  | 777,895 |  |  |
Issuance of common stock to Series A convertible preferred stockholders under make-whole adjustment feature |  |  |  |  | $ 778 | (778) |  |
Issuance of common stock related to accrued dividends (in shares) |  |  |  |  | 68,815 |  |  |
Issuance of common stock related to accrued dividends |  |  |  |  | $ 69 | 1,148,238 |  | 1,148,307
Series A cumulative preferred dividend |  |  |  |  |  | (85,993) |  | (85,993)
Series A cumulative preferred dividend |  |  |  |  |  | (85,993) |  | (85,993)
Issuance of common stock and warrants, net of issuance costs (in shares) |  |  |  |  | 1,000,000 |  |  |
Issuance of common stock and warrants, net of issuance costs |  |  |  |  | $ 1,000 | 10,416,520 |  | 10,417,520
Common stock issued for advisory services (in shares) |  |  |  |  | 7,792 |  |  |
Common stock issued for advisory services |  |  |  |  | $ 8 | 49,992 |  | 50,000
Stock-based compensation expense |  |  |  |  |  | 1,221,591 |  | 1,221,591
Net loss |  |  |  |  |  |  | (18,369,810) | (18,369,810)
Balance (in shares) at Dec. 31, 2018 |  |  |  |  | 3,376,230 |  |  |
Balance at Dec. 31, 2018 |  |  |  |  | $ 3,377 | 95,532,881 | (79,924,699) | 15,611,559
Stock-based compensation expense |  |  |  |  |  | 515,762 |  | 515,762
Net loss |  |  |  |  |  |  | (11,799,379) | (11,799,379)
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs (in shares) |  |  |  |  | 12,688,276 |  |  |
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs |  |  |  |  | $ 12,688 | 11,905,207 |  | 11,917,895
Proceeds from warrants (in shares) |  | 17,415,859 |  |  |  |  |  |
Proceeds from warrants |  | $ 17,416 | $ 3,888,425 |  |  |  |  |
Balance (in shares) at Dec. 31, 2019 |  |  |  |  | 33,480,365 |  |  |
Balance at Dec. 31, 2019 |  |  |  |  | $ 33,481 | $ 111,824,859 | $ (91,724,078) | $ 20,134,262

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