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v3.20.4

Consolidated Statements of Changes in Stockholders' Equity - USD ($) | Common Stock [Member] | Additional Paid-in Capital [Member] | Retained Earnings [Member] | Total
--- | --- | --- | --- | ---
Balance (in shares) at Dec. 31, 2018 | 3,376,230 |  |  |
Balance at Dec. 31, 2018 | $ 3,377 | $ 95,532,881 | $ (79,924,699) | $ 15,611,559
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs (in shares) | 12,688,276 |  |  |
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs | $ 12,688 | 11,905,207 |  | 11,917,895
Issuance of common stock upon exercise of warrants (in shares) | 17,415,859 |  |  |
Issuance of common stock upon exercise of warrants | $ 17,416 | 3,871,009 |  | 3,888,425
Stock-based compensation expense |  | 515,762 |  | 515,762
Net loss |  |  | (11,799,379) | (11,799,379)
Balance (in shares) at Dec. 31, 2019 | 33,480,365 |  |  |
Balance at Dec. 31, 2019 | $ 33,481 | 111,824,859 | (91,724,078) | 20,134,262
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs (in shares) | 11,428,572 |  |  |
Issuance of common stock, pre-funded warrants and warrants, net of issuance costs | $ 11,429 | 10,330,202 |  | 10,341,631
Issuance of common stock upon exercise of warrants (in shares) | 19,106,504 |  |  |
Issuance of common stock upon exercise of warrants | $ 19,106 | 7,768,370 |  | 7,787,476
Stock-based compensation expense |  | 736,119 |  | 736,119
Net loss |  |  | (14,185,306) | (14,185,306)
Balance (in shares) at Dec. 31, 2020 | 64,015,441 |  |  |
Balance at Dec. 31, 2020 | $ 64,016 | $ 130,659,550 | $ (105,909,384) | $ 24,814,182

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