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Note 5 - Stockholders' Equity and Common Stock Warrants
 3 Months Ended
Mar. 31, 2021
Notes to Financial Statements  
Stockholders' Equity Note Disclosure [Text Block]
5.
Stockholders' Equity and Common Stock Warrants
 
February 2021
Common Stock Offering
 
In
February 2021,
the Company completed the
February 2021
Offering in which it offered and sold
33,658,538
shares of its common stock in an underwritten public offering for a purchase price to the public of
$1.025
per share, inclusive of shares offered and sold pursuant to the underwriter's fully-exercised
30
-day option to purchase additional shares. The
February 2021
Offering resulted in aggregate net proceeds to the Company of
$31.1
million, after deducting underwriting commissions, discounts, expenses and other offering costs. In addition, at the closings of the
February 2021
Offering, the Company issued to designees of the underwriter of the transaction warrants to purchase up to an aggregate of
1,682,927
shares of common stock. The underwriter warrants have an exercise price of
$1.28125
per share and a term of
five
years from the date of issuance.
 
Common Stock Warrants
 
As of
March 
31,
2021,
the Company had the following warrants to acquire shares of its common stock outstanding:
 
   
Outstanding
    
Range of exercise
price per share
Expiration dates
Common stock warrants issued in 2017 related to Series A convertible preferred stock offering
    
903,870
    
 
$33.30
 
March 2022
Common stock warrants issued in 2018 related to January 2018 Offering
    
1,181,421
    
$12.00 
-
$15.00
January 2023
Common stock warrants issued related to the May 2019 Offering
    
1,382,913
    
$5.00
-
$6.11875
May and
December 2024
Common stock warrants issued related to the November 2019 Offering
    
267,140
    
 
$0.35
 
May 2021 and
November 2024
Common stock warrants issued related to the December 2019 Offering
    
313,339
    
$0.4335
-
$0.6981
December 2024
and June 2025
Common stock warrants issued related to the May 2020 Offering
    
571,429
    
 
$1.31
 
March 2025
Common stock warrants issued related to the May 2020 Investor Warrant Exercise
    
250,000
    
 
$0.5938
 
November 2025
Common stock warrants issued related to the February 2021 Offering
    
1,682,927
    
 
$1.28
 
February 2026
     
6,553,039
    
 
 
 
 
 
During the
three
months ended
March 
31,
2021,
no
warrants expired, and warrants were exercised by multiple holders to purchase a total of
4,230,000
shares of the Company's common stock for aggregate proceeds of approximately
$2.2
million.