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Note 5 - Significant Agreements and Contracts (Details Textual) - USD ($) | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | ---
Aug. 31, 2014 | Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022 | Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023 | Jan. 31, 2023 | Dec. 31, 2022
Research and Development Expense |  | $ 1,791,487 | $ 330,543 | $ 5,583,149 | $ 955,784 |  |  |  |  |
Government Assistance, Amount, Cumulative |  |  |  |  |  |  |  |  | $ 21,000,000.0 |
Revenues |  | 1,526,482 | $ 0 | 4,654,294 | $ 0 |  |  |  |  |
Deferred Revenue, Current |  | 547,051 |  | 547,051 |  |  |  |  |  | $ 0
Vertex Option and License Agreement [Member] |  |  |  |  |  |  |  |  |  |
Research and Development Expense | $ 100,000 |  |  |  |  |  |  |  |  |
Contractual Obligation |  | 117,000,000.0 |  | 117,000,000.0 |  |  |  |  |  |
Payments for License Agreement | $ 100,000 |  |  |  |  |  |  |  |  |
National Institute of Aging Grant [Member] |  |  |  |  |  |  |  |  |  |
Government Assistance, Amount, Cumulative |  |  |  |  |  |  |  |  | $ 21,000,000.0 |
Revenues |  | 1,600,000 |  | 4,700,000 |  |  |  |  |  |
Proceeds From Grants |  |  |  | 5,200,000 |  |  |  |  |  |
Grant Funding Remaining |  | 15,800,000 |  | 15,800,000 |  |  |  |  |  |
Deferred Revenue, Current |  | $ 500,000 |  | $ 500,000 |  |  |  |  |  |
National Institute of Aging Grant [Member] | Forecast [Member] |  |  |  |  |  |  |  |  |  |
Government Assistance, Amount |  |  |  |  |  | $ 6,200,000 | $ 8,100,000 | $ 6,700,000 |  |

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