<SEC-DOCUMENT>0001437749-23-019881-index.html : 20230713
<SEC-HEADER>0001437749-23-019881.hdr.sgml : 20230713
<ACCEPTANCE-DATETIME>20230713163224
ACCESSION NUMBER:		0001437749-23-019881
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		16
FILED AS OF DATE:		20230713
DATE AS OF CHANGE:		20230713

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Diffusion Pharmaceuticals Inc.
		CENTRAL INDEX KEY:			0001053691
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				300645032
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-271823
		FILM NUMBER:		231087095

	BUSINESS ADDRESS:	
		STREET 1:		300 EAST MAIN STREET
		STREET 2:		SUITE 201
		CITY:			CHARLOTTESVILLE
		STATE:			VA
		ZIP:			22902
		BUSINESS PHONE:		(434) 220-0718

	MAIL ADDRESS:	
		STREET 1:		300 EAST MAIN STREET
		STREET 2:		SUITE 201
		CITY:			CHARLOTTESVILLE
		STATE:			VA
		ZIP:			22902

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	RestorGenex Corp
		DATE OF NAME CHANGE:	20140307

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Stratus Media Group, Inc
		DATE OF NAME CHANGE:	20080722

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	FERIS INTERNATIONAL, INC.
		DATE OF NAME CHANGE:	20080228
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B3
<SEQUENCE>1
<FILENAME>dffn20230712c_424b3.htm
<DESCRIPTION>FORM 424B3
<TEXT>
Document 1 - file: dffn20230712c_424b3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>cglogo.jpg
<TEXT>
Document 2 - file: cglogo.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>dp01.jpg
<TEXT>
Document 3 - file: dp01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>eippharma01.jpg
<TEXT>
Document 4 - file: eippharma01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>graph01.jpg
<TEXT>
Document 5 - file: graph01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>graph02.jpg
<TEXT>
Document 6 - file: graph02.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>graph04.jpg
<TEXT>
Document 7 - file: graph04.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>graph05.jpg
<TEXT>
Document 8 - file: graph05.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>graph07.jpg
<TEXT>
Document 9 - file: graph07.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>graph08.jpg
<TEXT>
Document 10 - file: graph08.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>graph09.jpg
<TEXT>
Document 11 - file: graph09.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>graph10.jpg
<TEXT>
Document 12 - file: graph10.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>graph11.jpg
<TEXT>
Document 13 - file: graph11.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>graph12.jpg
<TEXT>
Document 14 - file: graph12.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>15
<FILENAME>pic1.jpg
<TEXT>
Document 15 - file: pic1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>16
<FILENAME>pic2.jpg
<TEXT>
Document 16 - file: pic2.jpg

</DOCUMENT>
</SEC-DOCUMENT>