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Note 3 - Basis of Presentation and Summary of Significant Accounting Policies (Tables) | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2023 | Dec. 31, 2022
Notes Tables |  |
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] |
|  | March 31, |
|  | 2023 |  |  | 2022 |
Common stock warrants |  |  | 88,252 |  |  |  | 111,891 |
Stock options |  |  | 104,047 |  |  |  | 116,564 |
Unvested restricted stock awards |  |  | 2,910 |  |  |  | 5,182 |
|  |  | 195,209 |  |  |  | 233,637 |
|  | December 31, |
|  | 2022 |  |  | 2021 |
Common stock warrants |  |  | 111,891 |  |  |  | 129,989 |
Stock options |  |  | 140,040 |  |  |  | 72,454 |
Unvested restricted stock units |  |  | 3,652 |  |  |  | 5,509 |
|  |  | 255,583 |  |  |  | 207,952 |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482662/260-10-50-1 + Details
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