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Note 7 - Stockholders' Equity and Common Stock Warrants - Warrants Outstanding to Acquire Shares of Its Common Stock (10 Q) (Details) - $ / shares | Mar. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021
--- | --- | --- | ---
Common stock warrants, outstanding (in shares) | 88,252 | 111,891 |
Warrants Issued in Connection with May 2019 Public Offering [Member] |  |  |
Common stock warrants, outstanding (in shares) | 27,648 | 27,648 |
Warrants Issued in Connection with May 2019 Public Offering [Member] | Minimum [Member] |  |  |
Range of exercise price (in dollars per share) |  |  | $ 250.09
Warrants Issued in Connection with May 2019 Public Offering [Member] | Maximum [Member] |  |  |
Range of exercise price (in dollars per share) |  |  | 306.04
Warrants Issued in Connection with the November 2019 Offering [Member] |  |  |
Common stock warrants, outstanding (in shares) | 4,269 | 4,269 |
Range of exercise price (in dollars per share) | $ 17.51 | $ 17.51 |
Warrants Issued in Connection with the December 2019 Offering [Member] |  |  |
Common stock warrants, outstanding (in shares) | 6,264 | 6,264 |
Warrants Issued in Connection with the December 2019 Offering [Member] | Minimum [Member] |  |  |
Range of exercise price (in dollars per share) |  |  | $ 21.68
Warrants Issued in Connection with the December 2019 Offering [Member] | Maximum [Member] |  |  |
Range of exercise price (in dollars per share) | $ 34.92 |  |
The May 2020 Offering Warrants [Member] |  |  |
Common stock warrants, outstanding (in shares) | 11,424 | 11,424 |
Range of exercise price (in dollars per share) | $ 65.65 | $ 65.65 |
The May 2020 Investor Warrant Exercise [Member] |  |  |
Common stock warrants, outstanding (in shares) | 4,998 | 4,998 |
Range of exercise price (in dollars per share) | $ 29.7 | $ 29.70 |
Underwriter Warrants in Connection with the February 2021 Common Stock Offering [Member] |  |  |
Common stock warrants, outstanding (in shares) | 33,649 | 33,649 |
Range of exercise price (in dollars per share) | $ 64.08 | $ 64.08 |

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- Definition Exercise price per share or per unit of warrants or rights outstanding. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 505 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 3 -Publisher FASB -URI https://asc.fasb.org//1943274/2147481112/505-10-50-3 + Details
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